McGill University Thèses et mémoires par auteur commençant par Q

ObjectifsLes objectifs de cette étude sont d'explorer l'impact des symptômes du TDAH à l'âge adulte sur les infractions au volant (par exemple, utilisation de la ceinture de sécurité, utilisation du téléphone portable, virages illégaux, excès de vitesse, défaut de s’arrêter, défaut de céder le passage, non-respect des distances de sécurité, conduite imprudente, conduite en état d'ivresse) et les collisions de véhicules à moteur (CVM) chez les adultes atteints de TDAH et des témoins normaux appariés suivi prospectivement pendant 16 ans dans le cadre de l'étude de suivi du Traitement Multimodal du TDAH sur plusieurs sites (MTA). Le rôle des comorbidités …  Lire la suite

Generation loss contingencies in electric power systems result in a deviation of system frequency from nominal, a condition which must be corrected promptly in order to prevent further degradation of the power system. Automatic load-shedding using underfrequency relays is one of the techniques used to correct abnormal frequency deviations and prevent the risk of uncontrolled outages. If sufficient load is shed following a contingency to preserve interconnections and keep generators on-line, the system can be restored with relative speed and ease. On the other hand, if a declining frequency condition is not dealt with adequately, a cascading disconnection of generating …  Lire la suite

Microfluidic systems open up new possibilities for in vitro cell biology research, mainly due to their ability to control the cellular microenvironment at physiologically relevant spatiotemporal scales. As such, several microfluidic systems have been introduced for the generation of concentration gradients and have been used for cell chemotaxis studies. However, these methods typically involve a trade-off between temporal control of the gradient and minimizing the applied shear stresses on the cells, and often require culturing cells in micro-channels. In this dissertation, we develop microfluidic quadrupoles (MQs) and demonstrate their first use in a laboratory setting. Two MQs with different configurations …  Lire la suite

The poet Jamil Sidqi al-Zahawi (1863-1936) was the first and greatest thinker of modern Iraq, and the only Iraqi writer who has gained a wide reputation outside his country - in other Arab and Muslim lands and in Europe. After a traditional Islamic education, Zahawi fell under the influence of Western philosophy and science and became a free thinker, as well as cm ardent liberal and social reformer. He played a certain part in politics and in the Arab national movement both before and after the 1914-1918 war, but the importance of his work lay in the realm, not of …  Lire la suite

Complex diseases are common diseases influenced by a combination of numerous genetic as well as environmental factors. Omics data, including genomics, transcriptomics, proteomics, and metabolomics, have contributed to our understanding of the pathophysiology of complex diseases and their treatment. The molecular basis of psychiatric disorders is beginning to be understood under the lens of various genomic-wide association studies, and omics studies. Furthermore, advances in pharmacogenomics have uncovered the associations between omics and medications. However, current approaches still mainly involve the use of univariate approaches, and there is a need for multivariate approaches to extract further insights from omics data.In this …  Lire la suite

Load modeling and identification are important in power system stability analysis. This thesis tests and validates a stochastic dynamic load model, which has been accepted widely in academia but has not been tested using real PMU measurements data. Besides, three different methods, namely, the least square method, unscented Kalman filter method, and the nonlinear dynamic recursive method based on the Ornstein-Uhlenbeck process are tested and compared in identifying the load model parameters using the simulated data in IEEE 39-bus system. Also, the real PMU measurements collected from the GZB, SX, and WX substations in China Southern Power Grid are used …  Lire la suite

This thesis illustrates a systematic study of accelerated aging, a mild solid-state synthetic approach inspired by biomineralization (also known as mineral neogenesis or mineral weathering). Similar to mechanochemical milling, accelerated aging is a solvent-free and low energy method for metal organic materials synthesis. It is even more sustainable by avoiding the expensive mechanical mills and the dusty working environment. In this thesis, both main group and transitional metal oxides have been selected as reactants for accelerated aging reactions. Due to their different reactivity towards certain organic acids, solvent-free separation of these minerals has been proposed and demonstrated. By transferring the …  Lire la suite

While great efforts have been made in the electrical utility industry to engineer various stranded conductors with enhanced strength and vibrational characteristics, research devoted to understanding the complex mechanical behavior of complete conductors has been scarce, especially from a computational mechanics perspective. In the meanwhile, the long-lasting problem of conductor fretting fatigue becomes increasingly critical for overhead line design and maintenance, especially with the world-wide aging of electrical transmission grids. Aging of conductors contributes to significant degradation of their local fatigue strength, leading to drastic reduction of their service life. However, the complex mechanical response of stranded conductors cannot be …  Lire la suite

One of the most attractive applications of composite materials is in robot industry. The reason lies in the fact that lightweight composite materials with excellent performance can dramatically overcome the tricky conflict of simultaneously achieving high end-effector positional accuracy and high link acceleration. This thesis describes the process of analysis and redesign of an anthropomorphic parallel robotic manipulator using graphite/epoxy fiber reinforced composites, which exhibit high stiffness-to-weight ratio and strength-to-weight ratio as well as good damping properties. From the structural viewpoint, by means of finite element analysis, the research into the composite robot arms covers the following aspects: redesign and …  Lire la suite

La perte du phosphore des terrains agricoles par l'écoulement de l'eau est l'une des problèmes environnementaux sérieux qui aboutit aux problèmes de qualité de l'eau telle que l'eutrophisation. Afin de résoudre ce problème, premièrement, les méthodes et les équations reliées à la perte de phosphore par le drainage souterrain dans les différents modèles de qualité de l'eau ont été examinées. Il a été conclu que huit modèles actuelles (ADAPT, ANIMO, APEX, HYDRUS, ICECREAM, MACRO, PLEASE, SWAP) sont capables de simuler le transport du phosphore au drainage souterrain basé sur leurs équations. ICECREAM prend l'origine de GLEAMS et CREAMS, ayant été …  Lire la suite

Early hearing screening and diagnosis in newborns are important in order to avoid problems with language acquisition and psychosocial development. Current newborn hearing screening tests cannot effectively distinguish conductive hearing loss from sensorineural hearing loss, which requires different medical approaches. Tympanometry is a fast and accurate hearing test routinely used for the examination of conductive hearing loss for older children and adults; however, the tympanograms are hard to interpret for newborns and infants younger than seven months old due to significant differences in the outer and middle ear. In this work, we used the finite-element method (FEM) to investigate the …  Lire la suite

The interaction between the glycolytic metabolism and fatty acid and glycerolipid biosynthesis in pea root (Pisum sativum L.) plastids was assessed in this study. When various glycolytic intermediates were used to substitute for the APT requirement for fatty acid synthesis from acetate, phosphoenolpyruvate, 2-phosphoglycerate, fructose-6-phosphate and glucose-6-phosphate each gave 48, 17, 23 and 17%, respectively, of the ATP-control activity. Similarly, in the absence of exogenously supplied ATP, the optimized triose-phosphate shuttle, which consists of 2 mM dihydroxyacetone phosphate, 2 mM oxaloacetic acid and 4 mM inorganic phosphate, gave up to 44% the ATP-control activity in promoting fatty acid synthesis from …  Lire la suite

In this study, the function and regulation of Rab-A1 proteins are investigated in the model plant species Arabidopsis. Rab proteins are a family of small Ras-like GTPases that regulate the vesicle transport during membrane trafficking. The subfamily of Rab-A proteins, homologues of Ypt31/32 in yeast and Rab11 in animals, is greatly elaborated in plants. In Arabidopsis, 26 out of 57 putative Rab proteins are Rab-A members and they can be further categorized into 6 subclasses from Rab-A1 to Rab-A6. The unique radiation of the Rab-A subfamily in the plant lineage is thought to be a mechanism to meet the dynamic …  Lire la suite

Shih, Ishiang (Internal/Supervisor)  Lire la suite

Lambda production in central Au+Au collisions at 11.5 A·GeV/c has been studied at forward rapidities (y > 2.2) using the upgraded E877 experimental setup at the AGS. Lambdas are measured via the charged decay channel: Λ → ppi- and identified from the ppi - invariant mass spectra with the aids of a set of pair cuts. A comprehensive Monte Carlo simulation is made to extensively study the lambda reconstruction. The details of the data analysis for lambda identification are presented. The consistence of data analysis is examined by detailed comparison of the constructed proton and pion spectra with the previous …  Lire la suite

Cette th\`ese traite du probl\`eme de surmonter les difficult\'es caus\'ees par l'effet de parallaxe et le mouvement d'objets lors du mosaicage d'images. Les m\'ethodes traditionnelles de mosaicage d'images produisent des panoramas en recalant des images de mani\`ere \`a minimiser les diff\'erences d'intensit\'e ou de structure entre les r\'egions superpos\'ees de ces images. Afin de r\'eduire les d\'efauts occasionn\'es par un mauvais recalage r\'esultant de l'effet de parallaxe ou des mouvements d'objets, les m\'ethodes traditionnelles requi\`erent soit une sc\`ene planaire, soit des images r\'esultant d'une simple rotation d'une camera, soit encore un \'echantillonnage dense de la sc\`ene. Toutefois, ces solutions sont …  Lire la suite

Colloidal polypyrrole and polyaniline stabilized by anionic surfactants were prepared and characterized. A "pseudo-micelle" model has been proposed. The aggregation of pseudo-micelles on the forming polymer chains is believed to be the key step in the stabilization process. Only when the aggregation is possible and fast enough to follow the polymer formation, will the polymer be stabilized. Colloidal polypyrrole and polyaniline were prepared in the presence of the sodium salt of poly(styrene sulfonate). The polymerization is believed to follow a template-guided fashion in which poly(styrene sulfonate) functions as a molecular template for pyrrole and aniline polymerization. The stability and water …  Lire la suite

L’identification précoce de la perte auditive est importante car si elle n’est pas traitée, elle peut entraîner un retard du développement du langage et d’autres difficultés. Les outils actuels de dépistage auditif du nouveau-né sont soumis à des taux de faux positifs excessivement élevés. La tympanométrie est un outil prometteur pour améliorer les tests de dépistage en évaluant l’état de l’oreille moyenne, mais elle est mal comprise chez les nouveau-nés. La tympanométrie implique de grandes déformations, des réponses non linéaires, des effets viscoélastiques (dépendants du temps) et des réponses dynamiques complexes, ce qui rend la modélisation difficile. Un précédent modèle …  Lire la suite

Ce mémoire étudie la conception d'un système de navigation autonome précis pour les véhicules terrestres et aériens dans les environnements sans GPS. Les méthodes actuelles de localisation et cartographie simultanées (SLAM) sont souvent appliquées à des situations spécifiques et leurs performances sont dictées par l'environnement qui est exploré. L'approche proposée utilise une correlation précise des balayages LIDAR et tente de mieux s'adapter à différents environnements en reliant différents types de points d'intérêt. Un nouvel estimateur optimal linéaire d'attitude et de translation utilisant des poids (WOLATE) est d'abord dérivé et utilisé comme algorithme de base pour enregistrer des nuages de points. …  Lire la suite

Java programs are deployed in a bytecode format that is executed by a Java virtual machine (JVM). JVM performance is determined by several major components: execution engine, garbage collector, and threading system. The static compilation and optimization approach, such as taken in C/C++ compilers, does not fit in Java's execution model very well because Java allows dynamic class loading, lazy resolution, just-in-time (JIT) compilation, and garbage collection. These dynamic features presents new challenges to JVM designers. In this thesis, we study both the challenges and opportunities of dynamic optimizations in Java virtual machines. Our contributions include a new garbage collector …  Lire la suite

We present a new approach to eliminate array bounds checks in Java by using static analyses. Our approach is based upon a flow-sensitive intraprocedural analysis called variable constraint analysis (VCA). VCA collects constraints between locals related to array references. The array bounds check problem is formulated as solving a system of difference constraints. The analysis builds a small constraint graph for each important point in a method, and then computes the shortest-path weight of the graph. The shortest-path weights from upper bound to array index and from the index to lower bound indicates the safety of checks. Using VCA as …  Lire la suite

Four experiments were conducted with the objectives of (i) comparing the suitability of various H. bulbosum clones for haploid production, (ii) determining the parental effects of H. bulbosum and barley genotypes on percentage of pollinated florets yielding caryopses with rescuable embryos and on embryo viability, (iii) comparing different stages for embryo culture and caryopsis culture, and (iv) attempting to produce barley haploids directly from cultured immature caryopses. The results demonstrated: that reproductive characteristics of H. bulbosum clones varied with environmental conditions; that the hybrid H. bulbosum clones MBC-3 and MBC-4 were superior to their parents Cb2920 and Cb2929 as pollen …  Lire la suite

Interferon-inducible transmembrane proteins (IFITMs) restrict entry of many pH-dependent enveloped viruses such as Influenza A virus, dengue virus, hepatitis C virus, Ebola virus, and even non-enveloped virus such as Reovirus. These proteins are believed to have two transmembrane or intramembrane domains and prevent viral membrane fusion without relocating the virus to other sites or changing the pH of the endosome environment. Previously, our group reported that IFITMs inhibit human immunodeficiency virus type 1 (HIV-1), a virus that does not require access to endosome for entry. In this study, we set to provide more evidence for restriction at entry of a …  Lire la suite

Suissa, Samy (Internal/Cosupervisor2)  Lire la suite

Avec le développement remarquable des technologies d'intégration à très grande échelle (VLSI), la variabilité des paramètres physiques et géométriques des appareils électroniques jouera un rôle plus important dans le fonctionnement des systèmes électroniques. Le phénomène nous demande de nous concentrer sur l'influence de ces incertitudes dans les circuits électroniques. Dans la littérature mathématique, la prédiction des effets de la variabilité est connue sous le nom de quantification de l'incertitude. Dans l'industrie actuelle, l'analyse de Monte Carlo est la méthode la plus populaire et la plus facile à mettre en œuvre. Cependant, d'un autre côté, il prend également beaucoup de temps …  Lire la suite

Dans un contexte d'interculturalisme québécois, cette recherche qualitative décrit et analyse les moyens à travers lesquelles parents et jeunes adultes immigrants chinois développent leur identité. Les fondements théoriques de cet ouvrage reposent sur les travaux de Hall (1990, 1996), Taylor (1994) et Bhabha (1996). Quinze entretiens individuels en profondeur ont été conduits auprès de parents et jeunes adultes au sein de cinq familles d'immigrants chinois vivantes à Montréal. Cette méthode a été utilisée afin de comprendre le vécu des sujets à partir de leurs expériences. Cette recherche tente de contribuer à une compréhension plus nuancée de la dynamique et de …  Lire la suite

Les composés d'azocarboxylate d'aryle restent sous-utilisés en tant que blocs de construction synthétiques, malgré le développement considérable de leur réactivité. L'un des facteurs contribuant à ce phénomène est la méthode de synthèse limitée pour accéder à cette classe de composés, limitant la portée des azocarboxylates d'aryle disponibles. La méthode dominante pour synthétiser l’azocarboxylate d’aryle implique la diazotation des anilines, la réduction en aryl hydrazines, suivie d'une substitution nucléophile en aryl hydrazides et l'oxydation en aryl azocarboxylates. Pour relever ce défi, nous avons développé une nouvelle stratégie pour accéder aux motifs azocarboxylate d'aryle à partir d'un processus de condensation entre des …  Lire la suite

A Latin square L of order n is an n × n array filled with elements of {1,2,...,n} such that each value appears exactly once in each column and each row. A critical set in a Latin square is a minimal set of entries that uniquely identifies it among all Latin squares of the same size. It is conjectured by Nelder in 1979, and later independently by Mahmoodian, and Bate and van Rees that the size of the smallest critical set is ⌊n2/4⌋.We confirm the quadratic order predicted by this conjecture by establishing a lower-bound of n^2/104 for sufficiently large …  Lire la suite

Urban vitality refers to the multiple social, economic, and environmental forces that contribute to the survival of a city and promote equitable development. Traditional assessments of urban vitality hinged on static metrics of building characteristics and often ignored the ever-evolving dynamics of human activities. It is argued that a city's characteristics are the individual flows of people. By looking at shared micromobility, this dissertation goes further than mere description to explore the temporal relationship between movement and place, as well as the causal processes driving changes to urban rhythms. The study presents a three-layered conceptual framework for the high-resolution mobility …  Lire la suite

This thesis develops a Bayesian Traffic Assignment (BTA) framework that represents network traffic conditions through a full probability distribution of link flows, rather than a single deterministic equilibrium. Building on the Conditional Stochastic User Equilibrium (CSUE) formulation, we express route choices probabilistically and derive the resulting equilibrium distribution of flows. To make inference feasible on realistic networks, we design a scalableblocked Markov Chain Monte Carlo (MCMC) sampler that updates travelers’ route choices in OD-based blocks and uses adaptive route-set regeneration.Using the Sioux Falls network as a case study, we show that the posterior mean flows align closely with classical deterministic …  Lire la suite

Spherical shells are ubiquitous in nature and engineering for their simple geometry and excellent load-bearing capacity. A long-standing topic of spherical shells subject to uniform external pressure is their highly unstable post-buckling response that leads to a catastrophic collapse. This type of failure fully exhausts the load-bearing capacity of the shell, and it is thus detrimental for traditional engineering applications. On the other hand, recent advances in soft robotics and metamaterials demonstrate that geometric nonlinearities and elastic instabilities can be harnessed to generate distinctive functions, such as shape morphing, fast motion, and logic operation.This thesis proposes the use of a …  Lire la suite

Few early modern religious groups inspired as much universal derision as the Ranters. Indeed, all competing confessions active in Interregnum and Restoration England unanimously lambasted them for their libertinism, drunken ecstasies, denial of sin’s existence, and ostensible 'madness', effectively casting them as the antitheses of seventeenth-century conventions of sociability. Yet could such societal pariahs ever become sociable? Seeking to rectify existing scholarship’s inattention to this question, this thesis investigates how former Ranters negotiated with their scandalous pasts and grappled with prevailing conventions of sociability after their movement’s suppression by 1651. It contends that erstwhile associates of the Ranter milieu reaccepted, …  Lire la suite

A general treatment which includes special cases of the five poses planar four-bar synthesis problem is investigated. There are 0, 2, or 4 real solutions to this problem formulated with five simultaneous equations. This method exposes solutions containing RR, PR, or RP dyads. The kinematic mapping is used to represent planar constraint equations in a three-dimensional projective image space because it offers a comprehensive way to solve problems in kinematic synthesis. The motion of a planar rigid body under a RR constraint can be mapped to points on a skew one-sheet hyperboloid with circles as generators which are generated by …  Lire la suite

La tendance de l'augmentation de la frequence d'operation et la diminution de la taille des appareils cause les circuits a ^etre de plus en plus complexe. Les effets des interconnexions exposent des problemes varies au sujet de l'integrite des signaux avec les signaux haute frequence. Les problemes d'integrites negligees peuvent ^etre importants et peuvent resulter en une mauvaise conception. Des techniques de modele sophistiquees existent mais produisent des grandes macromodeles. Pour reduire le co^ut de conception iterative et produire de bonnes conceptions au marche rapidement, des modeles de reduction d'ordre des modeles sont utilise dans beaucoup des outils avances de …  Lire la suite

The purpose of this study was to develop a method to differentiate muscle co-contraction from crosstalk in surface EMG recordings through muscle conduction velocity (CV) detection. A device was designed and constructed to measure surface EMG for detecting CV. This device was used to monitor the activity from the antagonist muscle when the subject tracked torque commands isometrically around the ankle. CV detected from the surface EMG was used as an indication of antagonist muscle co-activation; surface EMG recordings not showing CV were confirmed as crosstalk. As the result, CV was detected in the surface EMG from the antagonist muscle …  Lire la suite

The high and rapidly increasing demand for more telecommunication capacity and internet services drives the evolution of fiber optic communication. The third telecom window, which utilizes wavelengths around 1.5 μm and is widely utilized nowadays, can not meet this demand in future. Researchers are trying to develop technologies in new wavelength regions. Longer wavelength region has attracted intense interests for its prospective application. On the other hand, the fact that the wavelength region from 1.7 μm to 2 μm covers the absorption bands of water and greenhouse gas facilitates the applications in such area as sensing, spectroscopy and coherent LIDAR. …  Lire la suite

Le phosphore (P) est un important polluant de sources diffuses qui pourrait contribuer à l'eutrophication des eaux de surface. Dans cette étude, la capacité à simuler le débit de l'eau et le transport de P dans les sols argileux ou limon argileux du Sud de l'Ontario du modèle HYDRUS (2D/3D) a été évalué. Le modèle a été calibré et validé utilisant des données de terrain de deux parcelles d'essai de 0.1 ha entre 2008 et 2011. Ces parcelles ont contrôlées le drainage et la rotation des cultures de maïs et de soya. Les écoulements des eaux de surface et dans …  Lire la suite

Mazer, Bruce (Internal/Cosupervisor2)  Lire la suite

A novel dual-plasma process for the synthesis of organic layer-coated metal nanoparticles is presented. Metal nanoparticles are synthesized by the low-pressure pulsed arc evaporation of a metal cathode surface, followed by the in-flight deposition of a thin organic layer by capacitively-coupled radio-frequency (CCRF) plasma polymerization from a gaseous hydrocarbon monomer. The system is simple to operate and can be designed for high throughput. The combination of the synthesis and surface treatment of metal nanoparticles in the whole system avoids newly produced metal nanoparticles from being contaminated by surrounding environment. A home-made self-oscillatory pulsed power supply has been designed and built …  Lire la suite

In this dissertation, the phenomenology of electromagnetic radiation and high transverse momentum jets in relativistic heavy ion collisions is investigated. These are two very important probes to study the strongly interacting matter at extreme temperatures and/or densities and to investigate the possibility of a phase transition between hadronic matter and quark-gluon plasma (QGP). First, a new channel of direct photon production from a charge-asymmetric QGP is explored in the effective theory of quantum chromodynamics (QCD) at high temperature. The photon production from this new channel is found to be suppressed compared to QCD annihilation process and Compton scattering at low …  Lire la suite

Les télomères sont situés aux extrémités des chromosomes eucaryotes et se raccourcissent après chaque réplication de l'ADN, ce qui est l'une des causes du vieillissement cellulaire et contribue au vieillissement au niveau de l'organisme. Pour contrecarrer le raccourcissement des télomères, la plupart des organismes eucaryotes utilisent l'holoenzyme télomérase pour allonger les télomères. L'activité de la télomérase est absente dans les cellules somatiques humaines mais détectée dans les cellules souches, les cellules germinales et environ 85 % des cellules cancéreuses. Deux des composants essentiels de la télomérase chez l'humain sont l'ARN de la télomérase humaine (hTR) qui contient la matrice nécessaire …  Lire la suite

Les services système sont les services nécessaires pour maintenir la stabilité et la fiabilité du fonctionnement d'un réseau électrique. Traditionnellement, les services système sont fournis par les grandes centrales électriques et l'appareillage électrique approprié; cependant, comme les technologies microréseau se sont améliorées, les chercheurs et les industries ont commencé à envisager de fournir ces services par les microréseaux. Cette thèse étudie la faisabilité économique de fournir des services système par le microréseau, en effectuant une analyse coûts-bénéfices pour un projet de microréseau avec la fourniture de services système considérée comme une fonction distincte. Trois services système typiques sont considérés dans …  Lire la suite

The development of the Internet and the emergence of audio compression technologies have contributed to the realization of making millions of music titles accessible to millions of users. Due to the extensive distribution of music, consumers are being presented with a problem of information overload, while the music industry is being faced with the challenge of personalized promotion and distribution. Music recommendation systems aim to ease the task of finding the music items that might interest the users by generating meaningful recommendations. The recommendation for music is different from those for books and movies, due to its low cost per …  Lire la suite

CONTEXTE: le diagnostic et le traitement précoces sont des éléments clés pour un contrôle efficace de la tuberculose (TB) en Chine ainsi que dans les autres régions du monde. OBJECTIFS: Conduire une revue systématique du délai entre l'apparition des symptômes de TB et l'initiation du traitement recommandé (par des recherches récentes) et résumer l'information disponible sur le comportement des patients qui recherchent le soin pour TB ainsi que les voies qu'ils entreprennent à la recherche du traitement en Chine. MÉTHODOLOGIE: Une revue systématique et une méta-analyse ont été conduites. Des recherches ont été menée dans les bases de données PubMed, …  Lire la suite

This thesis reports on the design and analysis of a novel robotic drive unit, intended as the driving kernel for multi-degree of freedom (dof) parallel manipulators. The transmission system of this unit features a planetary gear train and a ball-screw mechanism. Due to this special transmission design, two driving motors can be placed on the fixed base, thereby enhancing the load-carrying capacity of the robotic drive unit. Parallel robots constructed and actuated with the proposed units should exhibit higher load-carrying capacity and faster motion capability, as compared to existing drives. The conceptual design of the unit is first proposed, and …  Lire la suite

It has been hypothesized that the pathophysiology of chronic heart failure (CHF) may be due to a relative deficiency of atrial natriuretic factor (ANF) and/or blunted responsiveness to ANF in this state. The work presented in this thesis evaluates the role of ANF in rats with chronic moderate high-output heart failure by (1) characterizing plasma and tissue ANF levels, hemodynamics and renal function at different stages of the development of heart failure; (2) assessing the contribution of the atria and ventricles to plasma ANF levels; and (3) investigating the role of ANF and renin-angiotensin systems (RAS) in rats with aorto-caval …  Lire la suite

Four types of dolomites occur in the Middle Devonian Presqu'ile barrier: fine-crystalline, medium-crystalline, coarse-crystalline, and saddle. Fine-crystalline dolomite formed penecontemporaneously by Middle Devonian seawater, because it is interbedded with Muskeg anhydrite in the back-barrier facies, and has O and Sr isotopic values of Middle Devonian seawater signatures. Medium-crystalline dolomite is interpreted to have formed: (1) at shallow burial depths by fluids derived from compaction, as indicated by its depleted $ delta sp{18}$O values and slightly radiogenic $ sp{87}$Sr/$ sp{86}$Sr ratios; or (2) soon after deposition by Middle Devonian seawater derived from the Elk Point basin, as suggested by its spatial …  Lire la suite