McGill University Thèses et mémoires publiés en 1984

On a observé les enregistrements extra-cellulaires venant des neurones de l’hypothalamus médian pour démontrer les connexions avec l’éminence médiane, la tige pituitaire, le septum latéral, l’amygdale, la région pré-optique hypothalamique antérieure et “PAG”. Des programmes d’ordinateur interactifs et des programmes et données de base out été utilisés pour l’analyse des résultats. On a démontré que certain certains neurones tubéro-infundibulaires identifies par la projection de leur axone ver l’éminence médiane se divisent en plusieurs branches vers la tige pituitaire. […]  Lire la suite

Renaud, Leo P. (Supervisor)  Lire la suite

The CBC Current Affairs program Sunday Morning is used as a case study to develop an appropriate theory and conceptual apparatus for the understanding of the relationship between the organisation of news-production and news-product. This relation is first identified as critical to the field of mass media studies in general, and news-research in particular. On the basis of this review a new model of news-as-discourse is proposed. In the examination of the radio program Sunday Morning this model and its conceptual categories are further developed and linked with other research in the sociology of news, the structuralist analysis of narrative, …  Lire la suite

A system was developed to study membrane transport in isolated human fibroblast plasma membrane vesicles, avoiding potential complications of intracellular binding and metabolism in the intact cell. Ten-fold enrichment of plasma membranes after subcellular fractionation was confirmed with appropriate markers. Transport competence was established by the following criteria: osmotic sensitivity, stereospecificity, temperature dependence, sodium gradient stimulation, response to ions and ionophores, saturability, and exchange properties. Methotrexate uptake was osmotically sensitive, temperature sensitive, saturable, and inhibited by folinic acid and phosphate. Measurement of lysine uptake was complicated by binding and lack of sodium dependence, but was stimulated by an interior-negative membrane …  Lire la suite

Le dosage biochimique des récepteurs ostrogéniques dans les adénocarcinomes mammaires humains a un intérêt clinique bien établi, cependant la localisation cellulaire des sites de liaison aux œstrogènes dans ces tumeurs demeure incertaine. Les travaux décrits dans cette thèse ont permis d'identifier les sites de liaison de l'oestradiol au moyen de l'autoradiographie après incubation in vitro dans une série de 57 cas de lésions mammaires dont 17 étaient bénignes et 40 étaient des adénocarcinomes. Les résultats obtenus avec la méthode d'incubation in vitro se comparent favorablement avec ceux obtenus dans des études in vivo portant sur l'utérus de souris, un organe …  Lire la suite

Sixty-six chronic low back pain sufferers, recruited through the media, were randomly divided into three groups. Following an assessment consisting of psychological questionnaires, pain monitoring and measurement of paraspinal electromyogram (EMG), one group received paraspinal EMG biofeedback, and a second group received a placebo treatment. The third group received no intervention. Two further assessments were carried out on all groups immediately after and three months after treatment. All groups showed significant reductions in pain, anxiety, depression and paraspinal EMG, but there were no differences among the groups. A regression analysis failed to identify subject characteristics which predicted positive outcome in …  Lire la suite

This dissertation examines the changing nature of the child's perception of the relationship between text and its intended audience, the world it describes, and the type of information it contains. Texts generated in the form of stories by children 4, 5 and 6 years of age are studied over a period of eighteen months. A movement away from a dependence on both context and interaction with a listener is observed in the children's texts as they become attuned to the plurilocal and non-dyadic nature of the type of text they are producing. Awareness of the text's non-obtrusive character is linked …  Lire la suite

This study examined the contributions of different brain areas to several of the behavior effects of amphetamine. The drug was micro-injected into each of six discreet brain sites in rats and the effects on behavior were examined. Amphetamine's rewarding effects were studied using the conditioned place preference (CPP) paradigm. Animals that had received injections into the nucleus accumbens showed a CPP, suggesting a rewarding effect of the drug. No effect was produced by injections into the medial frontal cortex, medial or lateral parts of the caudate nucleus, amygdala or the region around the area postrema. A conditioned taste aversion (CTA) …  Lire la suite

A new method for the acetalization of carbonyl compounds using chlorotrimethylsilane under mild conditions is described. Carbonyl compounds are acetalized by ethylene glycol with chlorotrimethylsilane. Two isomeric methyl olivetolates were synthesised by the condensation of 1,3-bis(trimethylsiloxy)-1-methoxybutadiene with the corresponding electrophilic components. This reaction has clearly indicated the discriminative behaviour of 1,3-bis(trimethylsiloxy)-1-methoxybutadiene towards different electrophilic sites thus leading to regio-selectivity. A new method for the synthesis of olivetol is described. This method provides a shorter route to olivetol from acyclic precursors. A new synthesis of (DELTA)('1)-tetrahydrocannabinol is described. The synthesis is patterned after biogenetic considerations. A new method for the synthesis …  Lire la suite

The purpose of this study is to investigate the possibility of using the Bleached Kraft wastewater sludges as a sealant to a permeable soil structure which could contain these liquids. The sludges used are either self-contained in wastewater, produced from treatment processes, or from the addition of chemical coagulant to the wastewater. The mechanisms of the sludge sealing phenomena which were investigated individually are divided into physical, physico-chemical, biophysical and bio-physico-chemical types of seals. Coarse sand #24 was found suitable for this sealing study as a particle size cut. Among the types of sealings studied, the bio-physical type of seals …  Lire la suite

The aim of this thesis is to present coherently the theory of ringoids from a purely ring theoretical point of view. Chapter 1, 2 and 3 are devoted to extend the results in theory of non-commutative rings to ringoids. In Chapter 4 we characterize torsion theories in abelian categories by using techniques in topos theory. In Chapter 5 and 6 we apply the results in previous chapters to characterize torsion theories in ringoids and prove the additive Giraud's theorem.  Lire la suite