McGill University Thèses et mémoires publiés en 2004

The experimental investigation of blood flow using in vitro models is very important to derive relevant and quantitative information in order to understand the biomechanical conditions resulting from blood flow dynamics. Furthermore, such studies can help us analyze and evaluate flow disturbances caused by pathologies and by cardiovascular prostheses such as aortic valves and left ventricular assist devices (LVAD). For example, these disturbances can range from high shear flow regions causing blood hemolysis to low shear regions resulting in plaque deposition. Flow visualization studies represent a family of methods to study fluid flow through cardiovascular hydraulic models using blood analogs. …  Lire la suite

We investigate a particular type of geometry, namely median metric spaces. This encompasses median graphs, as well as simple combinatorial structures known as spaces with walls. The group-theoretic applications are towards the Kazhdan property and the Haagerup property.  Lire la suite

Whey protein isolates (WPI) have been indicated to have potent cholesterol lowering and antioxidative properties. Such effects, however, are not consistently observed, which could be the result of major differences in the processing, isolation and composition of WPI. Moreover, the mechanisms of action or the bioactive component(s) in WPI are poorly understood although the relatively high cysteine content in WPI has been suggested to play an important role. Although high dietary cysteine has been shown to lower plasma homocysteine concentrations, the impact of WPI in this regard has not been investigated. The overall objective of this thesis was to examine …  Lire la suite

A planar joint dyad consists of two rigid bodies connected by a P (prismatic) or R (revolute) joint and similarly connected to a fixed third body. The nature of the quadric constraint surface in the planar kinematic mapping image space is investigated. The geometric reasoning concerning why five points in the image space are sufficient to define an RR dyad and why four are enough to define the workspace of a PR or RP dyad is described, explained and exploited. A general algorithm that combines both type and dimensional design synthesis to the planar joint dyad hence to the five-position …  Lire la suite

Objective. To develop predictive models for positive outcomes of upper and lower endoscopies in children. Methods. Retrospective review of all endoscopies performed from January to December, 2000 at St. Justine Hospital. Predictive models for positive outcomes on endoscopy were constructed for upper and lower endoscopies separately using multiple logistic regression. Results. Age greater than 13 years, hematemesis, epigastric tenderness and hypoalbuminemia were significant predictors of positive upper endoscopies. Male sex, age and rectal bleeding were significant predictors of positive lower endoscopies. Both models were significant at p < 0.0001 yet their receiver operating curves indicated that a model with sensitivity …  Lire la suite

Detailed sequence stratigraphic analyses indicate that the lower Cretaceous Falher F unit is made up of 4 sandy/pebbly prograding parasequences labeled F1, F2, F3, and F4. Of the parasequences only F3 has a significant (>2m) thickness of conglomerate. Vertical lithological successions through a conglomeratic section suggest that the F3 pebbles were deposited on the upper shoreface and foreshore as part of a conformable, shoaling-upwards package of rocks. Detailed mapping, using core, well logs, production data and 3-D seismic, show that the conglomerates form a 4 km wide linear body deposited along a linear topographic trend. This topographic trend coincides with …  Lire la suite

Market demand for housing changes over time, in response to the wants and needs of both individuals and society. Changes in socio-demographics highlight the emergence of non-traditional households in Canada and influence the configuration of a house (or product) which meets buyers' individual requirements. In turn, this affects the design approach (or process). At the same time, society today requires sustainability in housing development, since building a house consumes large amounts of energy during construction and after occupancy. Technology that improves the cost and performance of housing has advanced over time. Although some innovative design and construction systems (or approaches) …  Lire la suite

The mammalian proprotein convertases (PCs) of the secretory pathway are calcium-dependent serine proteinases related to bacterial subtilisin and yeast Kexin. As Kexin and subtilisin, all basic aa-specific convertases contain a comparable N-terminal structure starting with a signal peptide followed by a prosegment and a conserved catalytic domain. The convertases possess additional domains at their C-terminus following the catalytic domain. All PCs exhibit a P-domain prior to the C-terminal architecture, which is specific to each convertase. Three of the basic-aa-specific convertases, furin, PACE4 and PC5 display the presence of a Cysteine-rich domain (CRD). The function of the CRD has not been …  Lire la suite

Over the last decade the law of judicial jurisdiction has undergone profound changes in Canada. Chief among the factors that prompted evolution is the recognition of fairness as a guiding principle in the elaboration of jurisdictional rules. This thesis presents the consequences such recognition has already had and should have on the granting of freezing measures, those specific provisional measures aimed at freezing a defendant's assets pending litigation. Having reviewed the freezing measures that can be obtained from Canadian courts, this thesis shows how concerns of fairness to the parties have questioned traditional grounds of jurisdiction and how it has …  Lire la suite

The study suggests that two domestic conditions are critical to foster opportunities for sustainable peace between formerly conflicting societies. The conditions are defined as social capital and political integration. These are explored in the context of Israeli and Palestinian societies following the signing of the Oslo Peace Accords in 1993 and through 1999, just one year prior to the outbreak of the al-Aqsa Intifada. Social capital refers to networks of association. Strong networks of relationship are important because they are positively associated with a community and/or society's ability to foster social cohesion, to problem-solve and cope with growing uncertainty such …  Lire la suite

This thesis discusses the prohibition of human cloning in contemporary Islamic legal discourse, which relies on two distinct doctrines: the first seeks support in the Qur'anic text, while the second depends on method of utilitarian legal hermeneutics (al-istiṣlaḥ ). These doctrines are examined by comparing them to the method that contemporary Islamic legal discourse adopts, namely, uṣul al-fiqh. When this is done, a discrepancy emerges in the first doctrine that traces this prohibition back to the text of revelation, which in turn requires further clarification of the foundations of hermeneutics in uṣul al-fiqh---identified here as textual and legislative consistency. For …  Lire la suite

We measure the electron density of a single Landau Level of a two-dimensional electron system (2DES) in a GaAs/AlGaAs heterostructure cleaved edge overgrown structure. Edge spectroscopy, which is a powerful technique to probe correlations in 2D systems, has been used. While the 2DEG shows typical fractional quantum Hall features from a many-particle behavior (Luttinger Liquid) at low tunneling voltages, to single particle characteristic at high voltages, which reflects the absence of a many-body state away from the Fermi level. At high enough voltages, the single particle characteristic induces an asymmetry when tunneling into the 2DEG compared to tunneling out of …  Lire la suite

There is interest, supported by successful field trials, in the use of satellite communications at the Ka band (30/20 GHz) and beyond to meet emerging demand for broadband interactive multimedia services. The key advantages of operation at Ka band are availability of bandwidth and favorable implications for terminal size, cost and mobility. We study two problems related to bandwidth management of the uplink in a multibeam, CDMA-based, GEO satellite. Our focus is on the delivery of data services with rigid constraints on bit-error rate and elastic constraints on data rate. The first of the two problems concerns the design of …  Lire la suite

Background. This thesis explores the link between travel and deep venous thrombosis (DVT). While it is biologically plausible that prolonged travel is an independent risk factor for venous thromboembolic disease (VTE), epidemiological data to date are conflicting. Aim. To determine whether there is a independent association between travel and DVT. Methods. This was a multi-center case control study. Consecutive patients presenting to the vascular laboratory with clinically suspected DVT were eligible to participate. Cases were patients with confirmed DVT; controls were patients who had DVT ruled out. Travel history and clinical characteristics were determined though standardized interviewer-administered questionnaire. Genetic testing …  Lire la suite

The Trk family of receptor tyrosine kinases is involved in synaptic plasticity and behavioral memory in mammals. Here, we report the discovery of a Trk-like receptor, termed ApTrkl, in Aplysia. We show that it is expressed in the sensory neurons, the locus for synaptic facilitation, a cellular model for memory formation. Serotonin, the facilitatory neurotransmitter, activates ApTrkl. Activation of ApTrkl leads to activation of ERK. Finally, inhibiting activation of ApTrkl with the Trk inhibitor K252a blocks serotonin-mediated activation of ERK, and a form of cell-wide long-term facilitation. Thus, transactivation of the receptor tyrosine kinase ApTrkl by serotonin is an essential …  Lire la suite

Hes1 and Hes6 are basic helix loop helix (bHLH) proteins with a similar structure, but opposite biological roles: Hes1 prevents the differentiation of neural progenitors into neurons, whereas Hes6 promotes neuronal differentiation. To elucidate the reasons for the different activities of Hes1 and Hes6, we have focused on structural elements that are specific to either Hes1 or Hes6. In particular, Hes6 contains a stretch of acidic amino acids ("acidic patch") N-terminal to the bHLH domain. Such an acidic patch is not present in Hes1. Based on previous studies showing that similar acidic patches play a role in regulating the dimerization …  Lire la suite

Katsarkas, A. (Supervisor)  Lire la suite

dsc-4(qm182), a mutation that suppresses the lengthened defecation cycle of clk-1 also suppresses the delay in germline development. dsc-4 encodes a putative orthologue of microsomal triglyceride transfer protein (MTP), a protein essential for the assembly and secretion of apo-B-containing low density lipoproteins (LDL). The effect of dsc-4 on clk-1(qm30), coupled to studies of apoB homologues in worms led to a model suggesting the possibility of using C. elegans in the study of LDL-like lipoprotein particles. The impact of the level of lipoproteins is particularly evident in the germline developmental rate of the worms. We report here a further elucidation of …  Lire la suite

This thesis is a study of one of the most important national statesmen, politicians, and economists in the history of Turkish republic: Celal Bayar. It will analyze his impact on the Turkish revolution and the evolution of the nation's politics. Celal Bayar, Turkey's third president did not fit the mold of his country's top politicians of the day. He was essentially different from all the other key players of his generation in terms of his background, education, experience, career path, and even length of life. Those who have written about him have for the most part been either uncritical admirers …  Lire la suite

A sophisticated and high tech form of state-to-foreign population diplomacy based on the use of the latest communication technologies has developed rapidly in recent years and has acquired an increasingly important position within a significant number of foreign affairs systems. Pioneered by the heavyweights of the international stage, the phenomenon has spread rapidly to secondary powers and is progressively extending itself to varying degrees to all states around the globe. This thesis grapples with the enigma raised by the brisk re-emergence of this foreign policy concentration by attempting to understand the reasons behind both the quantitative increase in public diplomacy …  Lire la suite

BLK has 43% sequence homology to BIK and an identical BH3 domain, a region that is critical for its proapoptotic activity, making it the strongest candidate mouse ortholog. In addition, the gene structures of these two proteins are similar in functional organization. BLK and BIK activate apoptosis in similar fashion in both human and mouse cell lines, dependent on the presence of a functional BH3 domain and active caspases. BLK, like BIK, is very unstable and can be stabilized by addition of pan caspase inhibitor, zVAD-fmk. In contrast to BIK, BLK is not upregulated by p53 at the RNA or …  Lire la suite

This research emerged from the belief that merely economic explanations of rent seeking were too narrow and an interdisciplinary approach was needed to understand historical structural factors that contribute to particularistic exchanges. Rent-seeking and particularistic ties are almost always explained from a strictly neoclassical perspective which tend to be reductionist approaches that fail to explain why some states will be rent-seeking while others will not. Moreover, other frameworks that analyze state-civil society interaction do so without taking into account particularistic state-civil society interaction. Thus, there is a need to explain such particularistic ties in a comparative institutional framework. My dissertation …  Lire la suite

Urokinase plasminogen activator (uPA) promotes tumor invasion and metastasis in several malignancies including breast and prostate cancer. High levels of uPA are associated with invasive and metastatic characteristics of cancer. I examined the differential regulation of uPA expression by DNA methylation in normal, hormone responsive and hormone insensitive human breast and prostate cancer cell lines. Lack of uPA expression in normal and hormone responsive cells is due to methylation of uPA promoter. Treatment of these cells with a demethylating agent resulted in induction of uPA, higher invasive capacity of the cells, and significant increase in tumor volume. These studies demonstrated …  Lire la suite

Freshwater ecosystems worldwide are being altered by multiple stressors. One of the most important stressors is biological invasion---the introduction of exotic species, which can contribute to the loss of native species. The effects of an introduced species are correlated with its abundance and typically vary across ecosystems, suggesting that its impact on native species is mediated by its environment, i.e. the physical habitat and the recipient community. However, there are few studies that explore the effects of environment on the interactions between exotic and native species. My thesis examines the influence of physical habitat variables and community interactions on the …  Lire la suite

In this thesis, we examine the Conjugate Gradient algorithm for solving self-adjoint positive definite linear systems in Cn . We generalize the algorithm by proving a convergence result of Conjugate Gradient for self-adjoint positive definite operators in an arbitrary Hilbert space H. Then, we use the Maple software for symbolic manipulation to implement a general version of Conjugate Gradient and to demonstrate, by examples, that the algorithm can be used directly to solve problems in Hilbert spaces other than Cn .  Lire la suite

Sediment cores in the North Atlantic show evidence of periodic large-scale ice discharge events between 60 kyr and 10 kyr before present. These so-called Heinrich Events (HEs) occurred with a typical period between 5 kyr and 10 kyr. During each HE, a significant amount of ice was discharged from the Laurentide ice sheet into the North Atlantic. This input of freshwater through the melting of icebergs is thought to have strongly reduced the strength of the Atlantic thermohaline circulation. One theory for HEs is that they are due to an internal oscillation of the ice sheet under constant forcing. This …  Lire la suite

"Sexual orientation" is increasingly used as a prohibited ground for discrimination. The aim of this thesis is to show that this notion is being challenged both at the theoretical and implementation level. As a ground, "sexual orientation" ought to be replaced by "sex", as meaning the social construction of biological sex, in other words, "gender". First, this thesis exposes the history of "sexual orientation", and then the problems faced by Canadian and international courts when trying to implement it. "Sexual orientation" is then analysed within the broader perspective of the traditional liberal discourse on minorities. That perspective shows that LGBT …  Lire la suite

This thesis proposes that Charles Taylor's notion of the 'dialogical human life'---or what I call 'dialogical being in the world'---can be expanded to include pedagogical and democratical aspects. Furthermore, given the collapse of foundational epistemologies, I propose that teacher fulfillment may be negotiated through 'hermeneutical understanding', which recognizes the participation of the knower ('I') in the known (the 'other'). Such hermeneutical understanding is achieved through acknowledging my 'dialogical, democratical and pedagogical being in the world' (my life) as an unfolding story, which connects present acts of understanding the 'other' (including the otherness of self) with the past and future vision …  Lire la suite

The B7.2 molecule, which is mainly expressed on antigen-presenting cells, is well known to provide a costimulatory signal for the initiation of antigen-specific T cell responses through its interaction with CD28 expressed on T cells. B7.2 also binds to CTLA-4 which, in contrast to CD28, is a negative regulator of T cell activation. Normally, tightly regulated expression of B7.2 ensures the transient availability of this costimulatory signal. Because blockade of the CD28 pathway was able to inhibit the activation of self-reactive T cells in several experimental models, it has been postulated that deregulated expression of B7.2 on antigen-presenting cells may …  Lire la suite

This thesis explores how concepts of "adolescence" and "adolescent psychopathology" have become salient among medical and lay communities in Pelotas, a small town in Rio Grande do Sul, Brazil's southernmost state. The concept of adolescence emerged throughout the 20th century in Western Europe and North America from various specialized fields, including evolutionary medicine, psychiatry, and developmental psychology. Within these sub-fields, adolescence came to refer to a transitional phase in the life span, and specifically, to the psychopathologies and psychological opportunities ensuing from what could potentially become a life-altering transformation. In the past two decades, this concept of adolescence has been …  Lire la suite

2',3'-Cyclic nucleotide 3'-phosphodiesterase is a protein highly expressed in oligodendrocytes in the central nervous system, and it is believed to be an important regulator of myelination. In this report, two aspects of CNP are investigated, each introduced in their own chapters. First, a possible interaction of CNP with Fyn tyrosine kinase during myelination is investigated. Fyn is an important factor known to be active during the process of myelination, and CNP contains a number of possible tyrosine phosphorylation sites. Furthermore, their presence in an isolated domain of cell membrane called lipid rafts, further strengthened the possibility of interaction. However, no …  Lire la suite

A ground-based radar refractivity mapping technique is used to measure water vapor near the surface during the International H2O Project in May and June, 2002 (IHOP_2002). Radar-measured refractivity is compared with refractivity estimated from surface station observations during this field experiment. Bias in radar and station refractivity is found to occur often when humidity is high. Possible reasons for this difference between radar and station observations are discussed. Most of the biases were associated either with inaccurate humidity observations by stations or with the small height difference of the two measurements. With confirming this last observation further during these wet …  Lire la suite

The Maasai of East Africa traditionally consume a diet of milk, meat, and blood. Previous studies have found the Maasai to suffer from vitamin A deficiency (VAD). This micronutrient deficiency compromises systemic immunity and increases morbidity and mortality. A semi-quantitative food frequency questionnaire (FFQ) was used to investigate the vitamin A intake of small Maasai children in Loita, Kenya. On average, children consumed 596mug/dayRAE from retinoid sources and 956mug/dayRAE when coupled with beta-carotene sources. The measles virus (MV) has yet to be eradicated from East Africa and remains a threat to young children. The Maasai have developed methods to deal …  Lire la suite

A study was conducted to determine if polyacrylamide (PAM) could be utilized as a best management practice to reduce soil erosion on forest road embankments. Experiments involving two different PAM application rates (10 and 20 kg/ha) were conducted using natural rainfall in 2001 and 2002 and indoor rainfall simulation. In 2001, PAM was combined with a broadcast application of grass seed. The study results suggest that PAM provided no statistically significant erosion control after natural rainfall on a loam soil. In the rainfall simulation experiments PAM applied at both 10 and 20 kg/ha significantly reduced soil erosion (by 75 and …  Lire la suite

Multiple organ dysfunction is the most common cause of late mortality in trauma patients. Despite adequate resuscitation, hemorrhagic shock may progress to a state of profound systemic inflammation where the polymorphonuclear neutrophil (PMN) plays a key role. Resuscitation with hypertonic saline (HTS) may modulate the host inflammatory response in hemorrhagic shock. A murine hemorrhagic shock model evaluated by cremaster intravital microscopy demonstrated significant in vivo attenuation of neutrophil rolling and adhesion to endothelium (EC) immediately after resuscitation with HTS, as compared to Ringer's lactate (RL). Concurrently, macromolecular leakage from the same post capillary venules was 45% lower in HTS animals. …  Lire la suite

Folate metabolism is compartmentalized between the cytoplasm and the mitochondria of mammalian cells. Certain folate-dependent enzymes are present in both of these compartments, such as methylenetetrahydrofolate dehydrogenases, which are required to interconvert one-carbon substituted tetra hydrofolates. In the cytoplasm, there is a trifunctional NADP-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase-synthetase (DCS). Its mitochondrial counterpart is a bifunctional NAD-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase (NMDMC), expressed during embryogenesis and in immortalized cells. A comparison of the 3' untranslated region of the NMDMC cDNA with the synthetase domain of the DCS cDNA and gene among different species have revealed significant regions of homology. This suggests that the mammalian mitochondrial …  Lire la suite

In my dissertation, I present Hermann Cohen's foundation for the history and philosophy of science. My investigation begins with Cohen's formulation of a neo-Kantian epistemology. I analyze Cohen's early work, especially his contributions to 19th century debates about the theory of knowledge. I conclude by examining Cohen's mature theory of science in two works, The Principle of the Infinitesimal Method and its History of 1883, and Cohen's extensive 1914 Introduction to Friedrich Lange's History of Materialism. In the former, Cohen gives an historical and philosophical analysis of the foundations of the infinitesimal method in mathematics. In the latter, Cohen presents …  Lire la suite

Obstructive sleep apnea (OSA) is a disease process characterized by collapse of the upper airway during periods of sleep leading to the cessation airflow despite persistent respiratory efforts. The aim of this research project is to investigate for associations and correlations between OSA and other clinical entities using two separate prospective studies. The initial objective was to evaluate the prevalence of laryngopharyngeal reflux (LPR) in patients with OSA. LPR was present in 26/28 (93%) of OSA patients. Moreover, there were significant correlations between LPR and OSA severity (eg. r = 0.57, p = 0.001). The second objective of this research …  Lire la suite

This qualitative study investigates the consequences of advancing three preschoolers into kindergarten in the province of Quebec, where the derogation exemption enables younger children to start school before they reach the age of admission of five years by September 30th. The rationale for this study came from an interest to discover the perspectives of the students, their teachers, and their parents on the topic of derogation. This study examines how these students, one in grade 4 and two in grade 6, feel about being the youngest in the class, and how teachers and parents perceive them as learners and socializers. …  Lire la suite

Early in the 20th Century, the design and construction of high-voltage overhead electric power lines began. In the nearly 100 years since those first lines were built, the progressive collapse of large numbers of structures has been a continuing problem. These large progressive collapses are known today as cascades. While not all structural failures result in cascades, longitudinal cascades begin with a failure in the structural system that maintains tension in the overhead wires. These failures are represented most simply by a broken wire. Broken wires cause dynamic loads on the towers much higher than the intact wire tensions. This …  Lire la suite

This thesis considers the figure of the metrosexual, a contemporary archetype of stylish masculinity that has received considerable attention in the global media. It traces the development of a style-conscious and consuming masculinity in the West since the eighteenth century, through the figures of the dandy, the playboy and the new man. It also traces the discourse that has emerged in relation to metrosexuality in the Western media, from its first mention to the present. The metrosexual represents a significant departure from the norms of Western masculinity, most notably in his relationship to the homosexual and homoerotic. This thesis considers …  Lire la suite

Conventionally, the era that begins after the death of celebrated Ottoman sultan Suleyman I in 1566 is seen as the beginning of Ottoman decline. In line with the decline paradigm, late sixteenth century is also accepted as a time of political turmoil. This period is characterized by constant power struggles among Ottoman ruling elite and the deterioration of the classical Ottoman political order. Concerning the rise of new power elite (favourites) in the court and bureaucracy vis-a-vis the decreasing power of the sultans and grand vezirs, "evil counsellors" and the inaccessibility of the Ottoman sultan were chronic themes in the …  Lire la suite

Regulation of chromatin structure involves histone modifications such as acetylation. Since 1996, the identification and characterization of histone acetyltransferases have had tremendous impact on our understanding of the molecular mechanisms related to eukaryotic gene regulation and human diseases associated with abnormal chromatin functions. The MYST family of histone acetyltransferases is very interesting because of their various biological functions. In agreement with the correlation between aberrant histone acetylation and cancer, the MYST family proteins MOZ and MORF are linked to leukemogenesis. Identification and characterization of a gene encoding a novel histone acetyltransferase were the goals of this thesis project. Human MORF …  Lire la suite

The objective of this thesis is to analyse the evolution of the concept of pleasure in the literature and the history of ideas of the beginning of the 18th Century in France, through the study of the upheaval of sensibility carried out by Prevost's worried hedonism. In order to better understand the progressive transition of the semantic and lexicological concept of pleasure in the theoritical literature, we examine the philosophical and moral treaties on pleasure as well as the definitions found in the dictionnaires of the time. The study then focuses on two novels by Prevost: L'Histoire du chevalier Des …  Lire la suite

The epsilon4 allele of apolipoprotein E is now a well-known risk factor for Alzheimer's disease, however there is still much to be learned of the physiology of apoE in the brain, throughout normal aging and AD. To better understand the neurobiology of apoE, the work included in this thesis has focused on some of the key relationships apoE holds with some proteins known or suggested to have a role in the etiology of Alzheimer's disease. The H2 allele of apolipoprotein C-I is associated with Alzheimer's disease (AD). To examine the possibility of a direct role for apoC-I in AD, we …  Lire la suite

Over the past few years, attachment theory has taken on increased significance in academic and professional discourse, particularly in the field of child welfare. While this appears to be a relatively new area of interest in social work, the history of attachment theory dates back over five decades. This thesis aims to identify some of the reasons behind the resurgence of attachment theory, in particular, in child welfare practice. This renewed interest in attachment theory is tied to the current social climate and context for social work practice. This context, it is argued, contributes to the tendency for attachment theory …  Lire la suite

The interception of a tactical ballistic missile (TBM) represents a great challenge to the guidance and control community as the maneuver potential of the TBM is almost in the same order as the interceptor missile. The maneuver advantage of the interceptor over the TBM being reduced, a new approach for estimation and guidance for the interception of a maneuvering TBM is presented in this research. The target is assumed to use its maneuvering potential by performing a single evasive bang-bang maneuver. A simple detection algorithm for an evasive maneuver of the target combined with the use of a multiple model …  Lire la suite

Lewis, D. J. (Supervisor)  Lire la suite

The aim of this comparative study of Novalis' Heinrich von Ofterdingen , Holderlin's Hyperion, and Schlegel's Lucinde is to develop a comprehensive overview of the role of woman in conceptions of male subjectivity in Early German Romanticism. The reading of the novels developed here examines the Early Romantic poetics with a specific view to the conceptualizations of woman contained therein. The Early Romantic 'Project' consists in the rewriting of the subject and the world in the medium of poetry. Tanscendental poetry, the fragment, allegory, and irony are intended to invoke the presence of an absence, that is the absolute. In …  Lire la suite

Seniors 75 years of age and older, the majority of whom live in the community, constitute a segment of the population that is vulnerable to loss of autonomy. Indeed many community dwelling seniors have difficulty performing daily living activities, such as bathing, toileting, walking, preparing meals and housekeeping. In the setting of a population based cohort study of community-dwelling seniors 75 years of age or older, we examined the effect of unmet needs for community services for activities of daily living (ADL) and instrumental activities of daily living (IADL) on health services utilization. Self-perceived unmet need status was determined using …  Lire la suite