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  • Boechler, Graham
    2014 — Electrostatic alignment of gold nanorod arrays in polymer
    Résumé

    Gold nanorod solutions absorb light strongly at specific wavelengths, due to plasmon resonances. The wavelength of peak absorption shifts depending on the refractive index of the solvent, which makes them ideal for optical biosensors. However, in solution multiple resonances are present because the nanorod orientation is random. Here, an attempt at developing a technique for creating an aligned nanorod sample is presented. A solution of gold nanorods suspended in liquid polymer was cured while exposed to an electric field. The samples were imaged using a near-field scanning optical microscope, which showed different morphologies for samples exposed to the field and …  Lire la suite

  • Boehner, Reginald S.
    1912 — The hydrolysis of gelatine by baryta ; The transformation of glutaminic acid into proline.
    Résumé

    Though a-pyrrolidinecarboxylic acid or proline occurs widely distributed in nature, it first, became knomn to chemists as a synthetic product. Inactive proline was first synthesizedby Willstatter (Ber. 33. 1160, 1900). He condensed monosodiomalonic ester with trimethylenedibromide to form l-brompropylmalonic ester. [...]  Lire la suite

  • Boelen, Charles L.
    1969 — Les réactions secondaires aux médicaments: approche épidemiologique et critique d’enquêtes
    Résumé

    Une revue assez étendue de. différents problèmes soulevés par les réactions secondaires aux médicaments a été entreprise. La littérature spécialisée a été revue et critiquée suivant un schéma d'étude épidémiolocique. Une enquête rétrospective menée dans deux hôpitaux universitaires de Montréal a éprouvé un nouveau système de détection des réactions secondaires aux medicaments. Des méthodes et des résultats des plus importantes études épidémiologiques sur le sujet ont été compares. En conclusion, certains aspects du problème des reactions médicamenteuses ont été nouvellement identifiés et certaines suggestions pour l'amélioration des procédés de recherché ont été avancés.  Lire la suite

  • Boenke, Morgan
    2012 — Terrestrial habitat and ecology of Fowler's toads (Anaxyrus Fowleri)
    Résumé

    Habitat loss is the primary driver of global amphibian declines and thus preserving habitat is our best hope for preserving species at risk. The habitat needs of amphibians are complex due to terrestrial and aquatic requirements throughout their life history. Many pond breeding amphibians spend the majority of their life cycle within terrestrial environments and thus terrestrial habitats are critical to their persistence. Cryptic and fossorial behavior makes observations of amphibians in terrestrial habitats difficult. Our knowledge of the terrestrial ecology of amphibians is therefore incredibly limited. I review the literature on habitat loss, amphibian declines and terrestrial habitat use …  Lire la suite

  • Boer, Roland
    1993 — Jameson and Jeroboam : a Marxist reading of 1 Kings 11-14, 3 Eeigns 11-14 and 2 Chronicles 10-13
    Résumé

    In this dissertation I apply the literary and cultural theory of Fredric Jameson to some biblical texts. In the first chapter I present Jameson's theory as a complex relationship between an effort to account for the pluralism of methods and interpretations (metacommentary) and a specific Marxist method, comprising three phases of interpretation. In chapter two I apply metacommentary and the Marxist method to 1 Kings 11-14, moving from a formal and ideological analysis to questions of class and economics in an imperial context. In chapter three the method is similarly applied to two reinterpretations of the Kings passage: 3 Reigns …  Lire la suite

  • Boerboom, Derek
    1995 — Subcellular localization and substrate specificity of the protein-tyrosine phosphatase MPTP
    Résumé

    In order to study the subcellular localization of the protein-tyrosine phosphatase MPTP, indirect immunofluorescence microscopy experiments were performed. The enzyme was thereby determined to localize almost exclusively to the nucleus. The nuclear localization signal was mapped by further immunofluorescence experiments performed with deletion mutants and $ beta$-galactosidase fusion constructs. The sequence $ rm sp{345}RKRIRED sp{351}$ was found to be capable and sufficient to localize MPTP and unrelated proteins to the nucleus, and a secondary domain was identified that is likely involved in mediating the nuclear retention of MPTP. To determine the in vivo functions of MPTP, its substrate specificity was …  Lire la suite

  • Boers, Jacobus Johannes
    1988 — An ecological study of a reef-associated zooplankton community of Barbados, West Indies /
    Résumé

    A reef-associated zooplankton community was monitored at weekly intervals for 53 weeks. Samples were collected from quadrats of dense coral cover using emergence net traps. The numerical and biomass fluctuations of 15 taxonomic groups, 7 size classes and 5 feeding groups of the community were determined both temporally and spatially. The community was composed of abundant and diverse taxa (81) with cyclopoid copepods being the most important taxon. Larger-sized fauna (e.g. amphipods, decapods, mysids, etc.) were the second most important abundance and biomass contributors. Size class analysis illustrated a bimodal size distribution spectrum. The well developed second mode of the …  Lire la suite

  • Boettcher, Brady
    2023 — Developing Maturity in DMIs and Mapping Tools
    Résumé

    Wanderley, Marcelo (Supervisor1)  Lire la suite

  • Boetzkes, Amanda
    2002 — Berlin in disorder : the representation of nature in the works of George Grosz
    Résumé

    George Grosz's paintings and drawings of Berlin during the Weimar period demonstrate a complex matrix of tensions between nature and the urban experience. In his work, mechanization, sexuality, gender and animality are recurring themes that cue the viewer to the profound anxiety that modernity had unleashed a chaotic force into the city. Using an ecofeminist analysis, I show how the disorder of the city was imagined as a primordial human condition in which a previously disavowed connection to nature was suddenly foregrounded. Though Grosz's renditions of Berlin scenes are ironic, they also revel in the demise of social order. In …  Lire la suite

  • Boetzkes, Amanda
    2006 — Beyond perception : the ethics of contemporary earth art
    Résumé

    This dissertation considers the aesthetic strategies and ethical implications of contemporary earth art. Drawing from feminist and ecological critiques of phenomenology, it posits that an ethical preoccupation with the earth is identifiable in works that stage the artist's inability to condense natural phenomena into an intelligible art object thereby evidencing the earth's excess beyond the field of perception. Contemporary earth art has the paradoxical goal of evoking the sensorial plenitude of the earth without representing it as such. The first chapter analyzes Robert Smithson's monumental sculpture, the Spiral Jetty (1970), and suggests that the artist deploys the emblem of the …  Lire la suite

  • Boga, Kaushik
    2016 — A stochastic computing implementation of the disparity energy model for depth perception
    Résumé

    Implementing neuromorphic algorithms is increasingly interesting as the error resilience and low-area, low-energy nature of biological systems becomes the potential solution for problems in robotics and artificial intelligence. While conventional digital methods are inefficient in implementing massively parallel systems, analog solutions are hard to design and program. Stochastic computing (SC) is a natural bridge that allows pseudo-analog computations in the digital domain using low-complexity hardware. However, large-scale SC systems traditionally suffered from long latencies, hence higher energy consumption. This thesis develops a VLSI architecture for an SC based binocular vision system based on a disparity-energy model that emulates the hierarchical …  Lire la suite

  • Bogajewska, Dorota
    2012 — Deeming a predatory spouse unworthy to inherit under Canadian Common Law
    Résumé

    Cette thèse expose l'injustice et les conséquences potentielles dans la common law canadienne des «mariages prédateurs» impliquant des personnes âgées. Dans les cas où un conjoint vulnérable, victime de manipulation dans le mariage, est indument influencé dans l'exécution d'un nouveau testament en faveur de son conjoint prédateur, cette thèse propose un recours en empêchant le conjoint prédateur d'hériter après la mort du conjoint victime. Cette proposition est développée à travers une étude comparative de la doctrine de l'influence indue du droit canadien et de ses équivalents du droit allemand. La «slayer rule» de la common law et la législation sur …  Lire la suite

  • Bogante, Jack Ralph.
    1927 — Government guarantee of bank deposits in Canada.
    Résumé

    One of the outstanding consequences of our modern civilization is that the economic phase of life predominates all others. The "profit" motive has become the basis of individual endeavour; money-making is the goal of the business man, the dream of the youth and the incentive to work. The steady progress in the direction of improving the financial and banking systems, and the widespread education of the people in the advantages rendered by the banks to the community, have meant a greater utilization of banking institutions. With this development, the question of currency and mediums of exchange have asswmed great importance. …  Lire la suite

  • Bogason, Olafur
    2018 — Modeling auto circuits containing typical nonlinear components with wave digital filters
    Résumé

    Musicians and audio producers like vintage audio gear and for good reasons. The most beloved songs and sounds of the past were made on gear that now has become vintage. Examples of such gear are guitar pedals and amplifiers used by Jimi Hendrix (e.g., the Arbiter Fuzz Face) and the Mini-Moog synthesizer used by numerous artists since its debut in 1969. Unfortunately vintage gear is often expensive, hard to come by, impractical to transport and difficult to maintain.In order to replicate audio circuits that produce the sounds that vintage gear is famous for, multiple techniques from both industry and academia …  Lire la suite

  • Bogdanowicz, Kasia
    1995 — Commercial arbitration between Canada and the United States and the effect of the NAFTA
    Résumé

    Commercial undertakings to arbitrate and arbitral awards are commonly recognized and enforced in both Canada and the United States. Chapter Eleven of the North American Free Trade Agreement (NAFTA), Investor-State Arbitration, now gives new meaning to the established arbitral regime. For the first time in any trade pact in the world to date, the NAFTA provides a mechanism by which a private investor may submit a claim against NAFTA Party government to dispute resolution through "binding" arbitration. This system not only established an innovative solution to a bureaucratic quandary by raising the investor onto a level playing field with a …  Lire la suite

  • Boger, Dellie Lee.
    1939 — Le noir dans le roman français.
    Résumé

    "In spite of all that is written, said, and done, this great, big, incontrovertible fact stands out-the Negro is progressing, and that disproves all the arguments in the world that he is incapable of progress." L'amélioration de l'état et de la position sociale des Noirs est un des faits les plus saisissants de notre vie d'aujourd'hui. Depuis le commencement du vingtième siècle, période plus libérale et plus tolérante que nulle autre auparavant envers le Noir, il commence à pénétrer dans tous les domaines de la pensée, de la vie intellectuelle, sociale et politique. Il reste beaucoup à faire, naturellement, car …  Lire la suite

  • Boghossian, Johnny
    2017 — Artisans of authenticity: the emergence and growth of markets for artisan cheese and wine in Quebec
    Résumé

    Alors même les recherches sur la construction sociale de nouveaux marchés s'accumulent, la littérature prend rarement en compte les communautés et les territoires où s'enracinent ces marchés. Cependant, des phénomènes intéressants apparaissent lorsqu'on resserre l'analyse sur l'encastrement des marchés dans des communautés spécifiques. Notamment, certains marchés, bien que très récents, finissent par s'inscrire dans l'histoire locale, et apparaissent comme authentiques et traditionnels. Cette thèse par article contribue à avancer nos connaissances en matière de construction de nouveaux marchés en mettant l'emphase sur la création de l' « authenticité » et sur l'influence des identités régionales. Un premier article propose une …  Lire la suite

  • Boghossian, Nayiri.
    1999 — A comparative study of specific performance provisions in the United Nations Convention on contracts for the international sale of goods /
    Résumé

    The United Nations Convention on Contracts for the International Sale of Goods (CISG), adopted in April 11, 1980, is an attempt to unify rules of international trade. A large number of states that represent a variety of legal systems and of degrees of development have adhered to this Convention. As a result of the divergence of approaches and rules in these systems, several issues were debated during the negotiations, among others the remedy of specific performance. This thesis examines the provisions regarding specific performance in the Convention in attempt to reveal the divergence of approaches between Common Law and Civil …  Lire la suite

  • Bogiaris-Thibault, Guillaume
    2011 — Machiavelli's political virtue
    Résumé

    This thesis aims at clarifying Machiavelli's notion of political virtue by having recourse to Machiavelli's opinion of the empirical value of historical data. Thus, it takes the Florentine Histories as a work that can be used as a tool in support of any interpretation of Machiavelli's virtue when it comes to its ethical substance. I contend that this virtue most closely resemble a moderately deontological system of ethics where necessity acts as the threshold-setter. In chapter two I compare the qualities and attributes of the best princes and republics in order to make the point that political virtue is the …  Lire la suite

  • Bognat, Adam
    2019 — Physics-based audio synthesis in computer graphics
    Résumé

    La synthèse audio basée sur la physique trouve des applications de plus en plus diverses dans les domaines de l'infographie et de l'animation. Les approches classiques basées sur la synthèse modale sont appropriées pour les simulations de sons de contact corps rigide et de grands objets déformables, mais sont mal adaptées à d'autres primitives telles que les tiges élastiques et les coques minces en raison des effets non linéaires liés aux grands déplacements et aux contraintes de calcul. coût associé à des mailles très raffinées. Dans cette thèse, nous décrivons un framework logiciel pour la simulation de tiges élastiques et …  Lire la suite

  • Bogoiavlenskaia, Anna.
    2001 — Suggestioni dantesche nel sistema poetico, teologico e politico di Vladimir Soloviov
    Résumé

    The main scope of this study consists in analyzing how the poetic and ideologic universe of Dante is implanted and transformed in the Russian culture of the late XIXth---early XXth century. Particular emphasis is made on the role of Dante's heritage in the philosophy and poetry of the first Russian philosopher and symbolist poet---Vladimir Soloviov, as well as on the further impact of dantesche images on some major representatives of the Russian Symbolist movement. This analysis will be done through a demonstration of major point of interference between Soloviov and Dante: these can be examples of direct influence (as is …  Lire la suite

  • Bogojeski, Jovanka
    2017 — Synthesis and characterization of novel self-delivering amino acid-RNA conjugates for the development of potent siRNA prodrugs
    Résumé

    Small interfering RNA (siRNA) has the ability to silence virtually any gene of interest. The canonical structure, however, is negatively charged and hydrophilic. It is thus repulsed by the negatively charged phosphodiesters of the cellular membrane and prevented from penetrating the lipophilic membrane core. The main goal of this thesis is to synthesize siRNA conjugates containing 2'-sugar modifications that reduce the overall negative charge of the molecule and cause its unassisted cellular uptake, and to utilize these modifications to synthesize a biolabile analogue (a promoiety) in a prodrug siRNA (proRNA) construct. To this end, RNA conjugates were synthesized containing various …  Lire la suite

  • Bogoroch, Rita.
    1950 — A theoretical and technical study of autography as a histological method for localization of radioactive elements
    Résumé

    An "autograph", also known as a "radioautograph", "autoradiography or "historadiograph", is the "signature" left by a radioactive particle in a photographic emulsion, and is, therefore, the visual evidence of the presence of radioactivity in the structure in contact with the photographic emulsion. Radioisotopes present in biological material may be detected in two ways: 1) chemically, using the Geiger counter method and 2) histologically, using the above photographic technique - autography. It is the latter technique, however, that not only reveals the presence of the radioisotope within the specimen but also allows the isotope to be traced to its precise site …  Lire la suite

  • Bogossian, Aline
    2011 — Family environment as the social context for parenting children with a neurodevelopmental disorder: a descriptive synthesis of the literature
    Résumé

    Ce projet vise à souligner de quelles façons les aspects de l'environnement familial influencent les pratiques parentales des parents d'enfants atteints de troubles neuro-développementales (TND). En se référant à des études sélectionnées à l'intérieur d'une recensement de la littérature systématique effectuée pour le projet "Parenting Matters !" et en utilisant un protocole de recherche ayant des critères d'inclusion et d'exclusion précises, ce projet vise à souligner les aspects les plus importants à considérer dans cette relation de variables. Un recensement de la littérature systématique a été réalisé sur la relation entre l'environnement familial et les pratiques parentales d'enfants atteints de …  Lire la suite

  • Bogossian, Aline
    2017 — Exploring 'father involvement' among caregiving fathers of children and youth with neurodisabilities
    Résumé

    Les connaissances sur les expériences des parents d'enfants atteints de troubles neurodéveloppementaux se sont développées rapidement au cours des trente dernières années. Pourtant, malgré des études plus approfondies, la recherche sur les «parents» et la «parentalité» est souvent neutre sur le plan du genre et reconnait moins les expériences parentales des pères. Cette thèse, issue du domaine du travail social, se compose de trois articles. Elle a été conçue pour explorer la façon dont les pères des enfants atteints de troubles neurodéveloppementaux conçoivent leur engagement auprès de leur enfant, avec le but d'approfondir les connaissances sur l'engagement des pères pour …  Lire la suite

  • Bogue, Robert
    2025 — Developing vegetation-based proxies for satellite detection of volcanic degassing
    Résumé

    Détecter les variations dans les émissions de gaz volcaniques est essentiel pour prévoir les éruptions. Le dioxyde de carbone (CO₂) figure parmi les gaz les plus importants pour identifier les premiers signes d'activité volcanique, mais il reste difficile à surveiller efficacement. Les méthodes au sol manquent souvent de la résolution spatiale et temporelle nécessaire pour détecter des variations subtiles de flux, tandis que les observations satellitaires sont limitées par les concentrations élevées de CO₂ atmosphérique qui masquent les signaux localisés. Pour surmonter ces obstacles, nous avons développé une approche alternative utilisant les observations satellitaires de la santé de la végétation …  Lire la suite

  • Bogusz, Edwina J.
    1995 — The mechanism of the depressant action of dextrin on pyrite
    Résumé

    The separation of minerals by flotation depends on the effectiveness of the reagents used. The performance of depressants is paramount in rejecting the undesirable minerals while maintaining acceptable recoveries of the desired mineral. Iron-bearing minerals are the main contaminants in many ores: their removal is critical. Several different types of depressants have been used for this purpose, many of which are toxic. A shift has been made toward more environmentally friendly reagents including starch and dextrin. The purpose of this thesis was to determine the depression mechanism of dextrin on pyrite. A number of techniques were applied to give insight …  Lire la suite

  • Bohan, Matthew
    2015 — The synthesis, characterization, and stability of yukonite: Implications in arsenic mobility
    Résumé

    The focus of this thesis is to investigate the stability of the mineral phase yukonite–a calcium ferric arsenate–which may be important in controlling arsenic pore water concentrations in mineral processing-derived tailings. Yukonite has been found in association with gold mine tailings in Nova Scotia and the Yukon Territory in Canada, and laboratory accelerated ageing experiments suggest yukonite may form ferric arsenate phases in the presence of gypsum. Hence, this work fills a void in knowledge regarding the solubility/stability of yukonite.The results of this thesis are presented in the form of two manuscripts. The first study describes the synthesis and characterization …  Lire la suite

  • Bohbot, Jonathan
    2016 — Mood detection and memory performance evaluation with body sensors
    Résumé

    Cette thèse fournit la conception d'une application Android capable de mesurer l'humeur et la performance de la mémoire de toute personne humaine. Cette application est destinée à un usage médical et à la recherche. L'application est conçue pour être facile à utiliser, rapide et fiable pour les utilisateurs de tous sexes et âges. L'application a de nombreuses fonctions utiles, comme la détection de l'humeur, l'évaluation de la performance de la mémoire, une section historique de l'humeur qui nous donne les valeurs en pourcentage de l'humeur (triste, heureux, calme) et de la performance de la mémoire, une section conseils de l'humeur …  Lire la suite

  • Bohemen, Justin
    2024 — Optimized lighting strategies to increase yield and chemical uniformity in Cannabis sativa
    Résumé

    L'uniformité des cannabinoïdes joue un rôle important sur la qualité et la valeur marchande du cannabis récréatif. La consommation d’énergie devient une préoccupation majeure car l’éclairage est l’un des principaux coûts des systèmes de production de cannabis en environnement contrôlé. L'objectif de cette étude est d'évaluer les stratégies d'éclairage pour maximiser le rendement et l'uniformité des cannabinoïdes dans les plantes de cannabis. Quatre traitements d'éclairage inclus une lampe horticole classique de sodium à haute pression (HPS) éclairage suspendue dont la lumière vient du haut, la lumière de diode électroluminescente (DEL) éclairage suspendue, HPS éclairage suspendue + intercalaire et DEL éclairage …  Lire la suite

  • Bohloul, Seyyedsaeed
    2017 — First-principles quantum transport and linear response modeling of nano-devices and materials
    Résumé

    In this thesis, we investigate first-principles quantum transport in nano-electronic devices and develop a novel ab-initio technique to study linear responses in materials. In the first part of this thesis, we employ the state-of-the-art NEGF-DFT method to investigate quantum transport behavior of nano-devices which provide solid solutions for further miniaturization of future electronics. In particular, our first-principles investigation incorporates multiple disorder scattering using coherent potential approximation (CPA) which results in a thorough physical picture of quantum transport in realistic devices containing wanted or unwanted impurity atoms. First, we studied impurity-limited mobility of mono-layer black phosphorus (MBP) which is a strong …  Lire la suite

  • Böhme, Reinhard Dietmar.
    1963 — The reaction of active nitrogen with methyl chloride and methyl cyanide.
    Résumé

    The reaction of active nitrogen with methyl chloride yielded mainly hydrogen chloride and hydrogen cyanide, together with smaller amounts of ethylene and cyanogen. The corresponding reaction with methyl cyanide yielded hydrogen cyanide as the main product, accompanied by smaller amounts of ethane and cyanogen. Plateau values were observed for the decomposition of methyl chloride and for the concomitant production of hydrogen cyanide. [...]  Lire la suite

  • Bohn, Steven R. (Steven Raymond)
    1990 — A Markov model for fatigue crack growth and the prediction of component reliability /
    Résumé

    This thesis presents a probabilistic model, specifically a nonhomogeneous Markov model, for the description of fatigue crack growth. This model is capable of predicting the statistics of crack growth, the mean crack size and the variance in the crack size, at future times given two empirically determined system parameters, $ lambda$ and $ kappa$, and an initial crack size distribution. Prior to the mathematical development of this model a brief review of existing crack growth models is presented. After the mathematical development of the model has been presented the results from a previous application in the study of pitting corrosion …  Lire la suite

  • Bohonos, Danielle
    2024 — Populism in Canada: Elite Rhetoric and the 2022 Freedom Convoy
    Résumé

    This thesis uses a dictionary approach to text-analysis in an attempt to answer whether there was a spillover of far-right rhetoric from the grassroots movement of the Freedom Convoy Protest into elite-level discourse in the House of Commons. I find that while there are some indications that this rhetoric did impact the speeches of Conservative Party leadership candidates, these results are not statistically significant and could be clarified with further research on the topic  Lire la suite

  • Bohoran, Dodderich
    1976 — Educational media and the teaching of geography
    Résumé

    This paper is submitted as an accompaniment to my thesis presentation of April 25, 1973 at McGill University, Montreal. A tape recording of the concert, along with this paper will be deposited in the McGill University Archives. Herewithin are notes relating to l} production, 2} performance conditions, 3} a general description of the tape part of the work, and 4) the participation of the group METAMUSIC, in my piece, Piece for Four Track Tape Recorder Canada Unlimited Number Two -subtitled Sam McGee, abbreviated as PFFTTRCUNTsSMc. Preceding the body of the paper are 1) a table of abbreviations and 2} explanation …  Lire la suite

  • Bohossian, Nora.
    2006 — A case of scientific fraud? : a statistical approach
    Résumé

    In 1986 Thereza Imanishi-Kari, then an assistant professor at the Massachusetts Institute of Technology, was at the peak of her career. She had just coauthored a paper in the prestigious journal Cell with David Baltimore, a Nobel laureate. Their research was exciting and their findings promising. Margot O'Toole, Imanishi-Kari's postdoctoral fellow at the time, was unable to reproduce some of the experimental results published in the paper and could not resolve this with her postdoctoral supervisor. Subsequently, O'Toole became convinced that there were serious errors in the paper and, shortly afterwards, the National Institutes of Health began officially investigating the …  Lire la suite

  • Boianju, Inga
    2025 — Carbonate deformation across the brittle-ductile transition and how it affects the architecture of thrust systems
    Résumé

    Continental thrust systems are responsible for mountain building and associated earthquake hazard. Carbonate and pelitic rocks dominate fault systems in shallow marine settings in both continental and subduction convergent plate boundaries, and are potential 'weak links' in the downgoing plates of low-latitude oceanic subduction zones. Exposed fold & thrust belts are excellent natural laboratories preserving records of diverse deformation processes. Study of these can test the interplay between brittle and ductile deformation, the different deformation mechanisms involved in ductile shearing, the effects of fluid alteration, and how these feedbacks ultimately control the structural architecture through embrittlement, affecting fault localisation. This …  Lire la suite

  • Boileau, Isabelle
    2005 — The Dopaminergic response to drugs of abuse in healthy humans : insights from [¹¹C]raclopride studies
    Résumé

    Radioligand to receptor binding assessed with Positron Emission Tomography (PET) can be used to investigate dopamine (DA) concentration in vivo . The present dissertation focuses on the use of the PET DA D 2/3 receptor ligand [11C]raclopride to study DA release following the administration of drugs of abuse: amphetamine and alcohol. A number of experimental animal paradigms have indicated that DA transmission is generally potently engaged by the acute administration of addictive drugs (Di Chiara and Imperato 1988; Weiss, Markou et al. 1992), deficient during drug withdrawal (Markou and Koob 1991; Schulteis, Markou et al. 1995; Epping-Jordan, Watkins et al. …  Lire la suite

  • Boileau, Julie
    2002 — Le Gargantua de Rabelais réécrit pour les enfants /
    Résumé

    Among all the works that the literary canon designates as "classics," the works of Francois Rabelais are certainly among those that were most, and for the longest time, censured and transformed by adapters and commentators. Literature for young readers, an ensemble of texts whose boundaries are defined by the target readership, is a veritable small industry which, having received a boost right after the Second World War, has not stopped growing since 1945. Nonetheless, the practice of adapting classical works in order to make them "accessible" for children has been current since the 19th century. The adaptations for young readers …  Lire la suite

  • Boileau, Meaghan
    2021 — Targeting and modelling stem cells in human acute myeloid leukemia progression and established disease
    Résumé

    Les leucémies aiguës myéloïdes (LAM) sont des maladies hématopoïétiques agressives avec un taux de mortalité élevé chez les enfants et les adultes. Malgré l’avancement des connaissances en génomique du cancer et le développement de nouvelles approches thérapeutiques, le traitement des LAM a peu évolué au cours des quatre dernières décennies. Les patients LAM sont susceptibles de rechuter, ce qui mène souvent à une maladie plus agressive. La rechute est largement attribuée à la chimiorésistance des cellules souches leucémiques (CSL) qui maintiennent la maladie. Il est nécessaire de développer des thérapies capables d’éradiquer les CSL afin d’obtenir une guérison durable. De …  Lire la suite