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1965 — The anatomy and neurosecretory system of the supraoesophageal ganglion of Hermodice Carunculata (Annelida: Polychaeta).Résumé
Hermodice carunculata (Pallas) is an Amphinomid po1ychaete commonly found throughout the Caribbean area (Marsden, 1960). It also occurs in the Gulf of Mexico (Hartman, 1951) and off the coast of southern Florida (Mullin, 1923). The family Amphinomidae includes the first species of annelids to be described from the Western Hemisphere. In the eighteenth century, some West Indian faunal collections were deposited in various museums of western Europe. At that time, a young physician, Peter Simon Pallas, became interested in these collections. [...] Lire la suite
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2012 — Induction of the epithelial polarizing cytokine interleukin-33 by the fungus «Cryptococcus neoformans» in genetically susceptible miceRésumé
Avec la prevalence de l'épidémie du SIDA, comprendre la reaction de l'hôte au champignon opportuniste pathogène Cryptococcus neoformans, responsable de 650,000 décès chaque année en Afrique sub-saharienne, est devenu un sujet de recherche profonde. Les connaissances actuelles suggèrent que la susceptibilité à la pneumonie de cryptocoque chez les souris et les humains se produit par l'intermédiaire des réponses allergiques de type TH2 d'inflammation pulmonaire, alors que la résistance est attribuableau développent d'une réponse TH1 dans les poumons. Les cytokines épithéliales polarisatrices comme thymic stromal lymphopoietin (TSLP), l'interleukine-25 (IL-25) et IL-33 sont impliqués dans l'inflammation allergique TH2 respiratoire, mais leur rôle … Lire la suite
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1992 — Substance P increases in vitro lymphokine-activated-killer (LAK) cell cytotoxicity against fresh colorectal cancer cellsRésumé
Brown, Rae A. (Supervisor) Lire la suite
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1931 — La Bretagne dans les lettres contemporaines.Résumé
King, L. (Supervisors) Lire la suite
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2017 — Toward an understanding of cooperative microRNA-mediated silencingRésumé
La régulation post-transcriptionelle de l'expression des gènes joue un rôle essentiel dans le développement animal et dans diverses pathologies. Cette régulation est principalement contrôlée par la région 3ʹUTR non traduite de l'ARN messager (ARNm). Les microARNs (miARNs) sont de courts ARN d'environ 21 nucléotides et lorsque le complexe associé (miRISC) s'apparie avec les 3ʹUTRs, une inhibition traductionnelle, la déadenylation et la dégradation des ARNm est initiée. Plusieurs protéines de liaisons à l'ARN (RBPs) régulent l'expression des gènes par des mécanismes similaires. L'étendue des interactions entre les 3ʹUTRs, les miARNs et les RBPs est à ce jour toujours mal comprise. Malgré … Lire la suite
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1999 — A critique of the biomedical model : the clash between physician and patient expectationsRésumé
Biomedicine evolved from art to science. Based on the science, biomedicine built its culture. The scientific biomedical culture cannot cope with individual needs expressed during a consultation. The doctor-patient relationship, more than a simple encounter where biomedicine can flex its muscles against a disease, is the expected moment where the patient's illness will be alleviated. The scientific construct "disease" has no correlation with the social construct "illness". Doctor and patient are, therefore, not in opposing fields but in different universes. It is time for a paradigm shift. Lire la suite
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1991 — Speaker-independent consonant classification with distinctive featuresRésumé
We study the problem of classifying stop and nasal consonants in continuous speech independently of the speaker. We consider some acoustic parameters computed from the auditory spectrogram, and other parameters computed from the speech waveform. The classification algorithm uses a recurrent multi-layer perceptron (MLP) with localized connections. The design of the classifier is motivated by knowledge in phonetics and in pattern recognition. We report experiments for the TIMIT database, using 343 speakers in the training set and 77 different speakers in the test set. Good performance is obtained when many acoustic parameters are fed to the MLP, and when the … Lire la suite
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2013 — Turning over, for 13 instruments, piano, electronic microtonal piano and electronicsRésumé
Turning Over is a 13-minute composition for 13 instruments, piano, electronic piano and pre-recorded electronics. A strong emphasis on harmony, representing the result of two years of research into various intonation theories of the 17th, 18th and 20th centuries, is reflected in the subtle variations in intonation between the equal-tempered acoustic instruments and the just-intonation tuning of the electronics as well as the electronic piano. The musical discourse reflects philosophical concerns regarding the concept of essence in music and its illusive nature – this translates into a musical form that is in a constant state of transformation. Lire la suite
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2021 — Water Security on First Nations Reserves in Ontario: Exploring the impact of source water protection, community location, and fiscal capacityRésumé
Chronic water insecurity on First Nations reserves is embedded in flawed and fragmented governance and chronic underfunding. These structural issues affect all First Nations communities yet some communities have access to clean drinking water and some do not. In this work, I ask: How can variation in First Nations communities’ access to clean drinking water in Ontario be explained? Through a mixed-methods approach, using expert interviews and statistical analysis, the insight that emerges most clearly is that remoteness matters. The research also reveals differences in the way water security is framed, ranging from a protecting against water-threats lens to a … Lire la suite
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1991 — Measurement and modelling of human target-directed reaching movementsRésumé
These studies examined motion trajectories and electromyographic (EMG) activity patterns during human horizontal reaching movements towards single- and double-step visual targets. These data were used to test and elaborate a model of two-joint planar arm movement based on the equilibrium point (EP) hypothesis or $ lambda$ model of motor control. This work aims to understand how reaching movements are planned and controlled by the nervous system. To this end, simulated trajectories and EMG patterns, generated with hypothetical central commands, were compared to empirical trajectories and EMG patterns. In general, the model was able to predict trajectories but was less successful … Lire la suite
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2001 — Pathways to resilience in First Nations youth from a remote community : a case for the ameliorative effects of intelligence and social perspective coordinationRésumé
Variables that promote resilience, adaptive functioning despite adversity, were examined in 37 First Nations adolescents from a remote region in Northern-Quebec. Intelligence, and social perspective coordination, the ability to negotiate the self's and other's points of view in social situations, were offered as moderators of the effect of stress on competence. Competence was defined as developmentally-appropriate functioning in academic, behavioural, and social domains, and stress was operationalized as a combination of negative life events and demographic stressors. Better intellectual functioning and perspective coordination abilities were commensurate with elevated levels of academic performance and positive classroom behaviours. Additionally, intelligence served a … Lire la suite
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2007 — A point of departure in the comparison of social and nonsocial visual orienting among persons with autism spectrum disorders /Résumé
A Posner-like visual orienting task was used to compare social and nonsocial endogenous orienting among children with Autism Spectrum Disorder (ASD) and typically developing children matched on nonverbal mental age of approximately 8.5 years. This comparison was accomplished in the visual modality to avoid cross-modality task demands and with a particular focus on equating the stimuli with regard to complexity as these factors may have influenced earlier findings of a social orienting impairment among persons with ASDs. Participants were asked to detect social (face) and nonsocial (mixed face) targets on the basis of social (hand point) and nonsocial (arrow) cues, … Lire la suite
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2008 — Rough-and-tumble play and the development of externalizing behaviourRésumé
Longitudinal research on externalizing disorders has demonstrated that the signs of this form of psychopathology emerge early in life. For example, physically aggressive behaviours can be first observed as early as 18 months of age. Most preschool-aged children develop the self-regulatory abilities to inhibit these problem behaviours and express their aggressive and competitive impulses in alternative, constructive ways. Some children do not develop these abilities and chronic psychosocial difficulties typically result. Several researchers have raised the possibility that Parent-child rough-and-tumble play (RTP) interactions give parents and children an opportunity to develop the child's self-regulatory abilities. Defined here as aggressive behaviours … Lire la suite
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2017 — Fabrication and characterization of Py/Pt ferromagnetic nanowires on diamondRésumé
Childress, Lilian (Internal/Cosupervisor2) Lire la suite
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2025 — Tumour necrosis factor inhibitors and serious infections in pregnant women with chronic inflammatory diseases and their offspringRésumé
Bernatsky, Sasha (Supervisor1) Lire la suite
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2019 — To name another life, already lived: blackness and queerness, in love and studyRésumé
Ce mémoire trace l'être-Noir et l'être-Queer en tant qu'objets de désir, plutôt qu'objets de connaissance. Ce faisant, il cherche à démontrer que tout objet de savoir est, au moment même de sa conceptualisation, toujours-déjà défini par les désirs et investissements de ses théoriciens. Dans son contenu, ce mémoire se tourne vers certaines tendances critiques récentes dans la théorie Noire et théorie Queer (l'Afro-Pessimisme, l'optimisme Noir, la négativité Queer et l'utopisme Queer) à travers les désirs et investissements divers selon lesquels chacune de ces tendances forment leur objet d'étude. En observant certains moments de lapsus, où se révèle dans ces théories … Lire la suite
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2001 — The dynamics of corporate growth /Résumé
Jorgensen, Jan (Supervisor) Lire la suite
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1939 — The nature and meaning of historical knowledge.Résumé
Words are strange things - they change their meanings so very frequently; or perhaps it is we who do the chang1ng. At times it seems as though each man has a different meaning, or at least a different shade or meaning, for the same word. This fact is what makes defining such a difficult task. "A good definition must be succ1nct, i.e. it must with the greatest possible conciseness of expression accurately and completely establish the concept. A definition delimits the meaning of a particular word which serves to indicate a particular phenomenon. In the definition the phenomenon as a … Lire la suite
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1924 — Growth-adhesive affinities of different forms of tissue; with special reference to peritoneal adhesions.Résumé
Stehle, R. (Supervisors) Lire la suite
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2021 — Can Biomarkers of Stress and Inflammation Explain Sensitivity to Physical Activity?Résumé
Stone, Laura (Supervisor2) Lire la suite
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2021 — Robust streaming PCA via percentile thresholdingRésumé
Stephens, David (Supervisor1) Lire la suite
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1997 — As good as dead? : terminating treatment of demented patientsRésumé
Elliott, Carl (Supervisor) Lire la suite
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2016 — A fertile abyss: an anthropology between climate change science and actionRésumé
Au cours des deux dernières décennies qui ont suivies les premières négociations internationales sur le climat, de nombreux penseurs et autres acteurs de la vie publique ont mis en évidence un écart entre des déclarations ambitieuses et des accords contraignants, entre expertise et activisme, entre la disponibilité de l'information et l'engagement, entre le savoir scientifique abstrait et des programmes politiques concrets—bref, un décalage entre les sciences du climat et l'action sur le climat. Utilisant cette observation comme point de départ, ce mémoire explore ce qui constitue « la science » et que signifie « agir » dans les deux contextes … Lire la suite
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2023 — Possibility in an era of climate change: Anthropology, knowledge, politicsRésumé
Rees, Tobias (Supervisor2) Lire la suite
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2025 — The effects of mindfulness and self-compassion on perceived occupational stress and mental health in Canadian police officersRésumé
La police est l’une des professions les plus stressantes qu’une personne puisse exercer. Le travail implique de longues heures, des horaires décalés, une exposition à des situations dangereuses et souvent imprévisibles, des cycles rapides entre des périodes de faible et de fort stress, des problèmes de santé physiologiques, des troubles mentaux, la bureaucratie, et plus récemment, des critiques de la part du public et des médias. Pourtant, des milliers de personnes du monde entier choisissent de poursuivre cette profession, nombre d’entre elles ayant pour objectif d’améliorer leurs communautés. En raison d’une exposition élevée à de nombreux dangers, les policiers courent … Lire la suite
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2000 — Child maltreatment : teachers' knowledge of risk, procedures and reportingRésumé
Sixty teachers from the Ottawa-Carleton region of Canada were surveyed to measure their knowledge of child maltreatment risk indicators, knowledge of reporting procedures, and the frequency of reporting sexual abuse, physical abuse, and neglect. Correlations did not support the hypothesis of a significant relationship between knowledge and actual reporting frequency. Multiple Regression analyses demonstrated that the knowledge of child maltreatment risk factors and the knowledge of reporting procedures were not predictive of reporting. It was found that the teachers sampled were very knowledgeable of the basic risk indicators of child maltreatment and reporting procedures and policy. However, the findings did … Lire la suite
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2005 — Mandatory legal representation for children in custody, access and child protection proceedingsRésumé
The principle 'best interests of the child' has been expanded by the legal community in recent years to apply to any matter involving children in family law proceedings. The weight ascribed to this principle, however, has been diluted. In custody, access and child protection cases, evidence of which custodial arrangements are in a child's interests are often presented by adult parties in prolonged and costly proceedings. The judge makes an order which is intended to meet the child's "best interests", in the child's absence. This paper first examines the historical and theoretical justifications for children's rights in Canadian and international … Lire la suite
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2015 — Exploring the long-term sustainability of a nursing best practice guidelines programRésumé
Semenic, Sonia Elizabeth (Supervisor1) Lire la suite
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2024 — Resuscitation of Viable but Non-Culturable Campylobacter jejuni in Embryonated Chicken EggsRésumé
Campylobacter jejuni is a foodborne pathogen that is the most frequent cause of bacterial gastroenteritis cases globally. C. jejuni can enter a viable but non-culturable (VBNC) state in unfavourable conditions whereby it becomes undetectable by using the conventional culture media. This is of particular concern due to its ability to resuscitate under suitable conditions and potentially infect consumers. The goal of this thesis project was to induce C. jejuni into the VBNC state through a variety of adverse conditions that could occur in the food industry and test their resuscitation capability in embryonated chicken eggs. Four C. jejuni strains were … Lire la suite
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2013 — Vita activa and the nature of economic enterprises: a political theory of the firmRésumé
Cette thèse considère que l'entreprise capitaliste contemporain peut être compris en termes politiques indépendants de son association avec les grands systèmes économiques ou politiques au sein duquel il est situé. Vue au travers d'un cadre d'Arendt de la polis athénienne et vita activa - et sa connexion aristotélicienne entre la nécessité et la non-liberté - il devient possible de comprendre l'entreprise dans une telle manière. L'élévation moderne du rôle économique du ménage au niveau de la société - concomitante avec l'émergence de l'État comme l'administration - se traduit par la production sociale plutôt qu'individuelle, de la satisfaction de la nécessité … Lire la suite
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2015 — The dynamic interaction of hand grip and ice hockey stick flexion during slap shots and wrist shotsRésumé
Ce projet a combiné des technologies précédemment utilisées (Zane, 2012, Hannon, 2011) dans le but d'éxaminer l'interaction dynamique entre les forces appliquées par la main sur le bâton et les forces de flexion du bâton lui-même lors du lancé frappé et du tir du poignet. Dix-huit sujets adultes mâles, tous joueurs de hockey (11 de haut calibre, HC et 7 de bas calibre, LC), ont été étudiés. Les sujets ont réalisés cinq lancés du poignet et cinq lancés frappés d'une position stationnaire, en utilisant trois bâtons de différente rigidité (flex 77, 87 et 102). Le tout fût réalisé sur une … Lire la suite
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2013 — Medical humanitarianism and its mutations: an ethnography of the African Medical and Research FoundationRésumé
Ce mémoire cherche à montrer que l'African Medical and Research Foundation (AMREF) constitue une « mutation » de l'humanitaire médical, aussi bien dans le temps (à travers l'histoire de l'organisation) que dans l'espace (de l'Europe, lieu d'origine de l'humanitaire jusqu'au siège social d'AMREF en Afrique de l'Est). Dans le cadre de ce projet, l'auteure a entrepris quatre mois de recherches de terrain auprès du personnel des bureaux d'AMREF au Kenya, entre Juin et Septembre 2012, faisant usage de méthodes de recherche telles que l'observation participante, des visites de terrains, et de la recherche d'archives. Le premier chapitre documente l'engagement de … Lire la suite
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2019 — Joking about the darkness: affect, queerness, and politics in the work of Amanda PalmerRésumé
Barg, Lisa (Internal/Cosupervisor2) Lire la suite
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2020 — Functional characterization of the interaction between Alkali Cation/Proton Exchanger SLC9A6/NHE6 and Cyclin Dependent Kinase 5 (CDK5)Résumé
Le Syndrome de Christianson (SC), une maladie génétique et rare lié au chromosome X, est causé par une mutation amenant une perte de fonction du SLC9A6/NHE6, un échangeur de cations alcalins et des protons. Une personne ayant cette maladie manifeste souvent des symptômes modérées à graves comme la déficience intellectuelle, l’épilepsie, l’ataxie, le comportement autistique et la neurodégénérescence. L’échangeur NHE6 est encodé par un gène largement exprimé dans le corps mais cette protéine est particulièrement abondante dans les céllules du système nerveux où elle se localise sur les vésicules le long de la voie de signalisation endosomale responsable du recyclage … Lire la suite
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2014 — Pharmacist-administered immunizations in British ColumbiaRésumé
Kaczorowski, Janusz (Internal/Supervisor) Lire la suite
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2002 — Anti-Christian polemic in early Islam : a translation and analysis of Abū 'Uthmān 'Amr B. Baḥr al-Jāḥiẓ's risāla : Radd 'alā al-Naṣārā (a reply to the Christians)Résumé
This study intends to examine a ninth century anti-Christian polemic work written by the great Muslim litterateur al-Jaḥiẓ. The historical background of the treatise is presented within the contexts of the early `Abbasid regime (750-900), the Christian communities of the time, the impact of the translation movement, the rise and development of polemic discourse between Muslims and Christians, and the life and works of al-Jaḥiẓ. The study provides the manuscript background of the letter along with a translation supplemented by the work of Joshua Finkel. The analysis of the work is limited to one section, which reflects al-Jaḥiẓ's most original … Lire la suite