McGill University Thèses et mémoires par auteur commençant par T

Razek, Tarek (Internal/Supervisor)  Lire la suite

Let T be a complete, first order theory in a countable language. We investigate certain nonisolation properties of types in small superstable theories. Also, we prove that T has 2$ sp aleph$o nonisomorphic countable models in the following cases. (A) T is strictly stable and the order type of rationals cannot be embedded into O(T) and there is no strictly stable group interpretable in T$ rm sp{ sp.q}.$ (B) T is superstable, the generic of every simple group definable in T$ rm sp{ sp.eq}$ is orthogonal to all NENI types and rm sup {U(p) vert p{ in}S(T) } geq omega …  Lire la suite

La transplantation d'îlots pancréatiques est un traitement prometteur pour les patients atteints de diabète de type 1. Elle réduit la nécessité d'administrer de l'insuline et améliore le contrôle de la glycémie chez les patients les plus gravement atteints. Au cours de cette intervention, les îlots sont perfusés dans le tissu hépatique par la veine porte, qui est un environnement hypoxique. De plus, la technique utilisée pour isoler les îlots des donneurs détruit la vascularisation interne des îlots. Étant donné que les îlots sont très vascularisés et enrichis en oxygène dans le pancréas, leur viabilité diminue considérablement après la transplantation. Ainsi, …  Lire la suite

Tne first, fundamental question asked of the work of an artist is this one -- does he find and collect and comminicate "reality"? And in the quality and sureness of his expressed insight lies his success or failure as an artist. The novel, the most independent, most elastic, most prodigious of literary forms, attains its object in the communication of a full, intense, complex awareness or vision of human life. "II faudrait reconnaitre que l'art du roman est, avant tout, une transpos ition du reel et non une reproduction du reel", states Franeois Mauriac.  Lire la suite

Khoutorsky, Arkady (Supervisor2)  Lire la suite

Douglas, Dr. Virginia  Lire la suite

'adénocarcinome du pancréas (PAC) a un taux de survie à 5 ans de seulement 8%. Malgré des décennies de recherche, les options de traitement pour la PAC sont limitées. À l'époque de la médecine génomique, l'identification des sous-types génomiques pouvant être utiles pour individualiser le traitement et améliorer les taux de survie pour les patients suscite un intérêt croissant. L’utilisation de l’immunothérapie est une nouvelle approche particulièrement efficace pour le traitement de certains types de cancers. En général, les tumeurs du pancréas sont considérées résistantes aux traitements à médiation immunitaire. Cependant, les tumeurs pancréatiques ayant un déficit en réparation de …  Lire la suite

Le développement de l'industrie aéronautique a conduit à la signature d'accords bilatéraux, qui jouent un rôle croissant comme instruments de négociation entre les Etats parties. L'accord sur le transport aérien signé entre l'Union Européenne et les Etats-Unis, est devenu un accord bilatéral de premier plan, qui marque une nouvelle ère de l'industrie aéronautique mondiale. De nombreux problèmes actuels controversés relatifs au domaine du transport aérien, pourraient normalement être résolus par des négociations exclusives entre les deux parties en présence. Les retombées positives de l'accord ont été prévues non seulement par les deux parties, mais également par les pays tiers. Cette …  Lire la suite

For patient-specific quality assurance of IMRT, a point dose measurement with an ionisation chamber and a relative dose distribution with film are performed. The use of ionisation chambers follows dosimetry protocols that only deal with reference beams, for which Spencer-Attix cavity theory is valid. However, IMRT and other recent radiation delivery techniques do not comply with these protocols. Therefore, the conversion of the dose to the chamber cavity to the dose to water becomes uncertain; and the geometrical details of the chamber, as well as the details of the delivery, are expected to be significant. In this thesis, a realistic …  Lire la suite

This thesis presents the research to develop a technical aid for the blind to perceive images such as a face or a scenery. The images scanned and explored interactively by touch through a probe mounted on the index finger of each hand. The pixel intensities of the image are displayed to the user as stereo auditory signals. For the study, the aid was implemented partly by using a personal computer, a computer graphics tablet, a digital-signal-processing board, and audio equipment. In addition, a Time-Multiplexer circuit was built to support inputs from two finger-probes which are made by using two styluses …  Lire la suite

Kimmins, Sarah (Internal/Supervisor)  Lire la suite

The problem of mixing of subsonic circular jets with stationary fluid and with a stream at right angle has been studied. The present knowledge and conventional methods of approach to this problem are described. Applying Elrod's momentum diffusion theory of heat conduction to the mixing of a circular jet issued to a stationary fluid, the velocity distribution in the mixing region has been calculated and compared to Corrsin's experiment, and proved to be not quite satisfactory, especially at distance near the jet orifice. [...]  Lire la suite

The pathophysiological origins of airway hyperresponsiveness (AHR) in asthma are unknown. The objectives of this thesis were to establish an association between AHR in an animal model of asthma and altered contractility of airway smooth muscle (ASM) and to elucidate changes in contractile signalling that could account for any observed differences in ASM contractility. The Fisher strain of rat is spontaneously hyperresponsive to methacholine inhalation challenge relative to Lewis rats. These inbred rat strains provide a model with which to study genetically-determined variations in airway smooth muscle that may underlie AHR. Fisher rats were found to be also hyperresponsive to …  Lire la suite

Reaching for objects is essential in powered wheelchair (PW) mobility. For PW users, learning how to navigate their PW to reach for objects safely, as in daily activities, is crucial to their quality of life. Training for such PW use is limited due to lack of dedicated space, time, or equipment. Addressing these issues, the McGill Immersive Wheelchair (miWe) simulator is a virtual reality (VR) system for teaching PW driving skills that runs on an ordinary computer. However, a practical and low-cost training tool for reaching tasks does not exist for the miWe or any other PW simulator. Objective: The …  Lire la suite

With extraordinary advancements in Natural Language Processing (NLP) and crosswords being more popular than ever, the current era of Machine Learning (ML) and NLP has reinvigorated interest in automating crossword solving. Crossword puzzles are intellectual games that are popular all over the world. To solve them, they require a large vocabularyand deductive reasoning. Crosswordclues are often less straightforward, involve many different types of reasoning, and could contain multiple different linguistic complexities. Furthermore, they are often considered an ideal testing ground for AI and NLP tasks as they are an abundant, diverse and validated type of data.In fact, they are often …  Lire la suite

The infrared spectra of 14 bacteria were recorded by Fourier Transform Infrared (FTIR) spectroscopy. The effects of changes in growth conditions, such as temperature, growth medium, and incubation time, sampling conditions on the reproducibility of the spectra were investigated. The spectra of bacteria suspended in saline solution, in D$ sb2$O-saline and on plate films were obtained and stored in separate spectral libraries. The application of library search routines for differentiation and identification of the 14 bacteria was investigated. The spectral regions used for the library search include 1750-1560 cm$ sp{-1}$ and 1480-960 cm$ sp{-1}$, which contain bands mainly associated with …  Lire la suite

Cell transformation and malignancy may modulate some regulatory parameters of DNA replication, resulting in altered features of initiation of DNA replication in these cells. The objectives of this research were to examine the possibility for tumor-specific DNA replication origins and activation of replication origins in human transformed cells. Conventional PCR was used to detect chromosomal activities of several known and putative replication origins in four human cell lines (HeLa, NSF, WI38 and SK-MG-1). Quantitative comparison of origin activities demonstrates that origins associated with c-myc and NOA3 were approximately twice as active in HeLa cells as in NSF cells. To test …  Lire la suite

Cette thèse s’intéresse à l’évolution de l’attitude de la Chine à l’égard de l’arbitrage international. Contrairement à l’approche conventionnelle axée sur la règle qui étudie l’attitude de la Chine à travers son adhérence à l’arbitrage international ou encore sa conformité aux normes et principes internationaux, cette thèse adopte une perspective transcivilisationnelle du processus de prise de décision afin d’esquisser le portrait des interactions de la Chine avec les cours et les tribunaux internationaux, ce qu’elle ressent, pense, dit et comment elle se conduit – dans le passé, le présent et le futur. Compte tenu de la période d’intervention, de l’impérialisme …  Lire la suite

La xérostomie, ou bouche sèche, est un symptôme courant de la radiothérapie associée au cancer de la tête et du cou et se caractérise par une réduction importante du débit salivaire. Le développement du traitement par extrait de cellules de la moelle osseuse (BMCE) (thérapie expérimentale) a été bien caractérisé dans les modèles murins. Alors que les protéines ont été déterminées comme ingrédient actif, le sous-ensemble principalement impliqué dans sa fonction de restauration est mal défini. Pour optimiser ce traitement, nous devons d'abord créer un modèle in vitro permettant de tester, à haut débit, pour les protéines actives – une …  Lire la suite

Sensory perception generates intrinsic cortical representations for sensory stimuli, which serve as the foundation for subsequent learning and memory processes. Typically, cortical representations drift over time, influenced by internal modulations from memory and attention and external adaptations to the changing context and environment. Cortical representations of isolated objects in artificial images have been explored within precise visual areas, but the representation and representational drift of naturalistic objects in natural scene images within distributed visual cortices remain unclear. In this thesis, we investigated the cortical representations of object categories by employing the Natural Scenes Dataset, a high-resolution, deeply sampled fMRI dataset …  Lire la suite

Les huiles essentielles (HE) ont une utilité potentielle en tant que conservateurs alimentaires naturels en raison de leurs propriétés antimicrobiennes et antioxydantes. Plusieurs tentatives ont été faites pour développer des emballages actifs incorporant des HE dans des matériaux polymères qui peuvent lentement libérer les composés actifs volatils sur la surface des aliments pour inhiber la croissance des micro-organismes pathogènes. Dans nos recherches, l'efficacité des huiles essentielles dans l'inhibition de la croissance de L. grayi, sélectionnée comme substitut moins pathogène de L. monocytogenes, a été étudiée in vitro et dans des tests de stockage avec des produits végétaux surgelés décongelés. De …  Lire la suite

Les jeunes apparaissent comme étant le groupe de population le plus vulnérable au VIH et au SIDA au niveau mondial. En Chine, ce sont les lycéens, qui parmi les jeunes, ont été identifiés comme un groupe à haut risque particulièrement touché par le SIDA et les relations hétérosexuelles non-protégées. Un travail de prévention effectif devrait se baser sur une meilleure compréhension de la dimension socioculturelle de la transmission du VIH et des MST (maladies sexuellement transmissibles) parmi eux et sur une conceptualisation adéquate de leur sexualité, ceci en allant au-delà des approches biomédicales et positivistes.Cette thèse fait la description d'une …  Lire la suite

Nous présentons une démonstration du célèbre théorème de décomposition hyperfinie de Hjorth [Hjo05], issue de Miller et Tserunyan dans [MT18], laquelle nous généralisons pour le cas quasi-pmp. Nous présentons également un tentative de définition du coût dans le cas des relations d’équivalence boréliennes dénombrables quasi-pmp, accompagnée de quelques résultats préliminaires découlant de cette définition  Lire la suite

Germinal centers (GCs) are specialized structures formed in secondary lymphoid tissues (SLTs) in response to foreign antigens and are crucial for mounting antigen-specific immune responses. GC reactions require interaction between several cell types in specialized microenvironments that drive B cell affinity maturation, class switching, and differentiation into memory B cells and antibody-secreting plasma cells. Originally described as an axonal-guidance molecule, PlexinB2 is expressed on multiple immune cell subsets including near ubiquitous expression on B cells, with specific upregulation on GC B cells. The functional significance of B-cell PlexinB2 expression is not fully elucidated in GC reactions. Here, we investigate the …  Lire la suite

Ernst, Pierre (Internal/Supervisor)  Lire la suite

The architectural modelling and dynamic analysis of business processes and information systems is an important and challenging task. A new methodology and system called Macrotec have been developed to comprehensively support this task. However, Macrotec in its pure form does not cope with all the informal documentation that is part of business modelling. Hypertext is well-suited as an approach for information management and presentation because of its generality, flexibility and ease of use. This work demonstrates the applicability of hypertext concepts to support the capturing, organization and presentation of informal documentation in business modelling. […]  Lire la suite

Ehrlicher, Allen (Supervisor2)  Lire la suite

Li, Shanling (Supervisor2)  Lire la suite

The accidental, or maybe not so accidental, equation of the Long $ rm lbrack TE rbrack$ with the dragon is a minor, yet in many ways symbolic, incident in Western European reinvention of China. This reinvention can be found in a wide variety of discourses, the authors of which range from Enlightenment philosophes to nineteenth-century political economists, to the recent Derrida, and from the even earlier Sir John Mandeville, Oliver Goldsmith, to Coleridge, to W. S. Landor and De Quincey. It covers all aspects of Chinese culture, including philosophy, religion, government, language, poetry, and folklore. This dissertation argues that the …  Lire la suite

Coffin, Garth H. (Advisor)  Lire la suite

The contribution of this thesis is divided into two folds. The first is the development of a prediction tool for uncontrollable dilution based on regression techniques, Artificial Neural Networks (ANN), Random Forest (RF), and Recurrent Neural Networks (RNN). Using these techniques, different predictive models were developed based on a data set of 99 stopes from an underground mine in North America. The primary mining method applied in this mine is longitudinal retreat long-hole with variations in specific stopes. An accurate predictive dilution model will help improve the economic assessment of each stope. The second contribution of this thesis is identifying …  Lire la suite

En prenant comme point de départ la notion de parasitisme, le présent mémoire cherche à interroger la frontière conceptuelle qui distingue l'identité d'un discours dit « philosophique » de l'identité d'un discours dit « littéraire ». Suite à une analyse de l'évolution historique et lexicale du terme « parasite », nous avons tenté de voir ce en quoi la dynamique relationnelle ambigüe et la perturbation communicationnelle qu'il implique sont, de par les enjeux simultanément éthiques et langagiers qu'elles soulèvent, propices à penser la relation entre ces deux identités discursives, ainsi que celle qu'entretient l'identité philosophique à sa métaphoricité. Nous avons …  Lire la suite

En menant une lecture herméneutique approfondie de deux chapitres du Mawāqiʿ al-nujūm wa-matāliʿ ahillat al-asrār wa-l-'ulūm (Le Crépuscule des étoiles et l’Ascension des croissants des secrets et des sciences) d’Ibn ʿArabī (m. 1240), cette étude propose une méthode de lecture en trois volets pour aborder Ibn ʿArabī. Cette méthode met en avant la manière dont Ibn ʿArabī s’appuie d’abord sur la tradition soufie, avant d’approfondir ses conceptions théosophiques, pour finalement mettre au défi la tradition savante soufie. Cela est présenté à travers trois études de cas : la première consiste en une analyse littéraire comparative avec le Kasr al-shahwatayn (Briser …  Lire la suite

Shaw, A. (Supervisor)  Lire la suite

Steacie, E. (Supervisors)  Lire la suite

Marino, Faleh Tamimi (Supervisor1)  Lire la suite

The investigation of exo-laccase production by selected fungal strains, including Coriolus hirsutus, Pleurotus pulmonarius and Chaetomium thermophilium, under liquid-state fermentation was investigated. Among the investigated fungal strains, C. hirsutus found to be the most appropriate one in term of its capacity to produce active exo-laccase in the presence of ethanol as the most appropriate inducer. The effects of carbon and nitrogen concentrations on the production of active laccase were also investigated, where 50 mM of glucose and 5 mM of ammonium chloride were found to be respectively, the optimized concentrations. The exo-crude enzymatic extract was recovered and concentrated by ultrafiltration; …  Lire la suite

The utility of focal-plane-array Fourier transform infrared (FPA-FTIR) spectroscopy as a rapid method for the differentiation of antibiotic resistant foodborne pathogens was studied. Optimum spectral acquisition and processing parameters as well as appropriate film thickness of bacterial films were empirically established for the discrimination between two Shigella species (S. flexneri and S sonnei) in order to optimize the scanning parameters of an FPA-FTIR spectrometer. A detailed study of the potential of FPA-FTIR spectroscopy for the discrimination between antibiotic resistant and sensitive strains from two Salmonella species (S. Typhimurium and S. Heidelberg) was subsequently undertaken. The results of these studies demonstrated …  Lire la suite

Philip, Anie (Supervisor2)  Lire la suite

Aircraft flight testing is an integral part of aircraft design and development. Flighttesting serves as a method to expand and verify the aircraft flight envelope, as well asdemonstrate adequate performance, stability, and systems compliance. It is a requirementof aircraft certification authorities to demonstrate aircraft safety and operability through themeans of flight test.In the past two decades, data collected during flight test has more than tripled as aircraftsystems became more complex and sensor technology improved. In addition to theincreased data collected per flight test hour, an aircraft program can require thousands offlight test hours before aircraft entry into service. Coupled with …  Lire la suite

Objectif : La simulation permet aux résidents des spécialités chirurgicales de pratiquer délibérément et de façon répétitive leurs compétences chirurgicales dans un environnement sécuritaire et sans risque. TSYM (Symgery, Montréal) est un simulateur de réalité virtuelle de chirurgie spinale. Le but de cette étude de série de cas est l’investigation de la validité de face, contenu et construit de la laminectomie lombaire simulée sur cette plateforme. Méthodes : Des consultants, des fellows et des résidents en neurochirurgie et chirurgie orthopédique ont participé à l'étude. Les participants ont été regroupés a priori en deux catégories : stagiaires (résidents en troisième cycle …  Lire la suite

This thesis attempts to integrate the divorce outcome data concerning children within the stress and coping mechanisms paradigm. The effects of divorce on children are reviewed, as are the major constructs of stress-coping theory. A study is conducted to demonstrate the empirical utility of the theoretical integration of the two domains. The coping resources, styles and efforts of 71 elementary school children from divorced and intact homes were investigated. Data analyses demonstrated that children from divorced homes had lower levels of psychological coping resources, and less effective coping styles and efforts, thus sustaining the theoretical integration. Other significant results revealed …  Lire la suite

This thesis is a survey of the Cauchy law. We begin by exploring its genesis and some of its most important properties. This leads us to particularize the Cauchy distribution by putting all together the most important characterizations available in the literature. Statistical inference based on the Cauchy distribution is then discussed. We end by taking a glance at some related distributions, the bivariate and multivariate Cauchy distribution.  Lire la suite

This study examines the concept of art education known as Discipline-based art education, (DBAE), from three vantage points. It begins by tracing the history and development of DBAE theory, and by examining its defining characteristics. It follows with a critical discussion of DBAE theory, specifically from within the context of multicultural education. The discussion then shifts to the realm of practice. The study describes a two week professional development program offered by the Minnesota DBAE Consortium, in Minneapolis, in the summer of 1995, and grounds the discussion in the results of questionnaires and interviews with six secondary school art specialists …  Lire la suite

Sabiston, Catherine (Internal/Cosupervisor2)  Lire la suite