Résumés
Résumé
Des études effectuées chez une population de volontaires sains en administration unique indiquent que les benzodiazépines (BZD) sont connues pour induire des déficits en mémoire. Cette population étudiée ne correspond toutefois pas avec celle qui consomme régulièrement ces substances soit les personnes âgées. Peu d’études ont été faites auprès de cette population cible afin de déterminer l’impact des BZD sur leur mémoire. Par contre, il existe des évidences suggérant aussi qu’il existe des conséquences importantes sur le fonctionnement de la mémoire des personnes âgées qui prennent des BZD. Les données actuelles vont même jusqu’à suggérer que les BZD exacerbent les déficits de mémoire chez les personnes âgées. Cela pourrait même constituer un facteur de risque précipitant le déclin cognitif et augmentant ainsi le risque de développer une démence.
Abstract
Studies conducted with a healthy voluntary population with a unique medication indicate that benzodiazepines (BZD) are known to induce memory deficits. However, this group does not correspond to the population usually using these medication on a regular basis, knowingly the elderly people. Few studies have been conducted with this target population to determine the impact of BZD on their memory. However, some findings suggest that there are important consequences on the functionning of memory of the elderly people taking BZD. The current data go as far as suggesting that BZD exacerbate memory deficits in the elderly. This could even constitute a risk factor that could hasten cognitive decline and thus increase development of dementia.
Resumen
Los estudios efectuados de una dosis única en una población de voluntarios sanos indican que las benzodiacepinas (BDZ) son conocidas por inducir déficit de memoria. Esta población estudiada no corresponde, sin embargo, a la que consume regularmente estas substancias, es decir, las personas de edad avanzada. Se han realizado pocos estudios en esta población objeto a fin de determinar el impacto de las BZD en la memoria. Sin embargo, existen evidencias que sugieren también que existen consecuencias importantes en el funcionamiento de la memoria de las personas de edad avanzada que toman BZD. Los datos actuales llegan a sugerir que las BZD exacerban los déficit de memoria en las personas de edad avanzada. Esto podría incluso constituir un factor de riesgo que precipita la decadencia cognitiva y aumenta de esta manera el riesgo de desarrollar demencia.
Resumo
Estudos efetuados em uma população de voluntários saudáveis em administração única indicam que as benzodiazepinas (BZD) são conhecidas por induzir déficits de memória. Entretanto, esta população estudada não é comparável à que consume regularmente estas substâncias, ou seja, as pessoas idosas. Poucos estudos foram realizados junto a esta população-alvo afim de determinar o impacto das BZD na memória. Por outro lado, existem evidências que também sugerem a existência de conseqüências importantes no funcionamento da memória das pessoas idosas que fazem uso das BZD. Os dados atuais chegam até a sugerir que as BZD aumentam os déficits de memória nas pessoas idosas. Isto poderia constituir um fator de risco levando ao declínio cognitivo e aumentando assim, o risco de desenvolver uma demência.
Parties annexes
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